Meredith Greer

@EmmGeezee

fellow, future fellow!, queso connoisseur, cat mom, forever Texan and Bonnaroovian. y’all👩‍⚕️🧀🐱🤠🦄

Atlanta, GA
Vrijeme pridruživanja: travanj 2017.

Tweetovi

Blokirali ste korisnika/cu @EmmGeezee

Jeste li sigurni da želite vidjeti te tweetove? Time nećete deblokirati korisnika/cu @EmmGeezee

  1. Prikvačeni tweet
    18. pro 2019.

    Goals for the new year: 1. Be nicer, always 2. CHILLLLLLLLL 3. Stop taking things so personally 4. CHILLLLLLLLL 5. Convince at least one medical student that the physical exam is meaningful

    Poništi
  2. prije 1 sat

    Why’s it gotta be this way First Aid?

    Poništi
  3. prije 7 sati
    Poništi
  4. prije 20 sati

    Ohhh boyyy first day of lung school tomorrow lettt's go! 🌬️

    Poništi
  5. 2. velj

    Things happening today that I care about, in order: 1. Palindrome Day (02022020) 2. Groundhog Day 3. Superb Owl Sunday 4. Actual Super Bowl

    Poništi
  6. 2. velj

    Haiii everyone good evening my IRB got approved and I just submitted my book chapter for review wowww y'all I am so relieved I can't even! Time for ! #🍷

    Poništi
  7. 31. sij

    To clarify, this is for large volume thora, the idea being that you don’t have to wait, are just draining to gravity, if it’s parapneumonic or there’s an incidental ptx then perfect you already have a tube in.

    Prikaži ovu nit
    Poništi
  8. 31. sij
    Prikaži ovu nit
    Poništi
  9. 31. sij

    I used West zones in real life last night and...

    Poništi
  10. 30. sij

    20/ Alright, I hope you found this helpful, please feel free to drop questions below, and if you’re interested in learning more here is a super helpful website! 🤓

    Prikaži ovu nit
    Poništi
  11. 30. sij

    19/ And in this case, if they do, ELISA is the next best step for differentiating PR3 vs MPO, but just remember – vasculitis isn’t the only thing that can cause a positive ANCA so BE WARY, and as always, .

    Prikaži ovu nit
    Poništi
  12. 30. sij

    18/ SO, when you order an ANCA (and please do this wisely), remember what you’re doing. Just dumping your patient’s blood on neutrophils that have all the things of a neutrophil (and also a cell) and seeing if any antibodies stick.

    Prikaži ovu nit
    Poništi
  13. 30. sij

    17/ These are abs to basically ANY of those neutrophilic enzymes, things like EGPA, drug-induced/associated vasculitis, Goodpasture’s, Buerger’s, CF, IBD, autoimmune hepatitis, (pre)eclampsia, subacute bacterial endocarditis, cGVHD, malaria, and even leprosy can cause +ANCAs!

    Prikaži ovu nit
    Poništi
  14. 30. sij

    16/ But you MIGHT think about ordering an ANA (IF CLINICALLY INDICATED ONLY AS ALWAYS, rheumies plz don’t hate me). As if things couldn’t get worse, there is a long list of things other than just AAV (GPA/MPA) and +ANA associated diseases that can cause positive ANCAs, remember:

    Prikaži ovu nit
    Poništi
  15. 30. sij

    15/ Well, what the heck do we do now?! Okay, either way, if you have a positive ANCA (c or p) you should do an ELISA test which will specify if it’s really PR3 or MPO. If you have a positive p-ANCA specifically, see if your lab does formalin comparison?

    Prikaži ovu nit
    Poništi
  16. 30. sij

    14/ If it’s perinuclear on ethanol but NOT on formalin, there’s a good chance that it’s an ANCA. If it’s “perinuclear” on both, then we might have an ANA on our hands, ie it’s actually in the nucleus. DISCLAIMER: I am deffo not addressing the cytoplasmic "ANAs" right now bc…

    Prikaži ovu nit
    Poništi
  17. 30. sij

    13/ Welp, turns out, formalin fixation does NOT make things positive and cuddle up next to the negative nucleus. SO if you’re REALLY feeling savvy, what you can do is dump your patient’s blood on some ethanol-neutrophils AND some formalin-neutrophils, and see what happens!

    Prikaži ovu nit
    Poništi
  18. 30. sij

    12/ So how do we know if these are really perinuclear or nuclear? UGH.

    Prikaži ovu nit
    Poništi
  19. 30. sij

    11/ While this is a great idea, it’s not always correct, and there are “in between” patterns as well, making things even more confusing. So, you’ve done your IF, and you got a positive p-ANCA using ethanol-fixation…but remember! There are antigens in the nucleus too ()...

    Prikaži ovu nit
    Poništi
  20. 30. sij

    10/ PR3 is not positively charged, so it remains chillin’ in the cytoplasm, hence it’s “cytoplasmic”.

    Prikaži ovu nit
    Poništi
  21. 30. sij

    9/ These aren’t just ANY neutrophils on a plate, they’re “ethanol fixed” neutrophils. What this does, is make all of the positively charged proteins in the cytoplasm migrate toward the nucleus as the nucleus is negatively charged. Like MOTHS TO A FLAME, MPO becomes “perinuclear”!

    Prikaži ovu nit
    Poništi

Čini se da učitavanje traje već neko vrijeme.

Twitter je možda preopterećen ili ima kratkotrajnih poteškoća u radu. Pokušajte ponovno ili potražite dodatne informacije u odjeljku Status Twittera.

    Možda bi vam se svidjelo i ovo:

    ·