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Prikvačeni tweet
Rheum4Debate
#podcast Ep.4 at http://ebrheum.com !@anisha_dua and@sarahfantus debate this motion: "In MTX non-responders with RA, triple therapy (adding HCQ & SSZ) should be first line" Vote the poll AFTER you listen! Whoever gains the most votes is declared the winnerHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Timely
@TheLancet case series of 41 pts w/the 2019 novel coronavirus, PMID: 31986264 1. Fever ubiquitous 2. Flu like symptoms common 3. Respiratory sx seem to drive outcomes Selection bias (hospitalized cohort) likely inflated mortality (15%); rate in all comers probably <5%pic.twitter.com/sGYVaieiGC
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Really nice editorial re:complications from therapy in ANCA-associated vasculitis Encouraging to note progress - previously 93% 2-year mortality! Comes at a price - 1/4 of patients develop infxn, typically early in tx course, and infxn #1 cause mortality Much still to do!pic.twitter.com/gxFO2PJ5cs
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NEW EULAR guidelines for RA, PMID 31969328 1. TtT!
2. MTX 1st line
3. More csDMARDs if no poor prognostic factors
4. Add bDMARD/JAKi if poor prognostic factors & csDMARD failure
5. IL6/JAKi if csDMARD not possible
Overall good. I try HCQ but typically skip #3pic.twitter.com/02wJ6BrSW1
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You probably also follow
@VPrasadMDMPH and already heard (https://overcast.fm/+ORIBxrY-0 ), but still: 1. Insightful thoughts about spending your time (improve yourself, address worthy problems) 2. Re:medical writers - “There is a simple rule.. you write papers... write it yourself”Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
NEW podcast, anifrolumab for SLE. I cover TULIP-1
@TheLancetRheum and TULIP-2@NEJM Interesting ?s, including multiple hypothesis testing, surrogate endpoints, and PROs. Let me know what you think after listening; share with friends! Subscribe at http://ebrheum.com pic.twitter.com/LVggCqSf2V
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NEW 2020 BSR Guidelines for GCA 1. Thoughtful algorithm for dx! 2. Long (12-18 mo) taper rec but allows for MTX/TCZ to shorten 3. Strong “can consider” TCZ; conditional “might consider” MTX https://tinyurl.com/wuctp3b Congrats
@Sarah_L_Mackie@cmukhtyar@petercgrayson!@RheumJnlpic.twitter.com/x3OSiMbyai
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TAKT RCT of TCZ vs PLBO in takayasu arteritis, 96wk open label extension just published PMID 31951279 Good GC taper/sparing, 86% improved imaging, & clinically important PROs met Can’t trust open label data; this is essentially a well funded cohort study. Still, nice to see!pic.twitter.com/ikGSN2qkT5
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VITAMINS RCT published in
@JAMA_current, open label VitC & thiamine vs none in septic shock, PMID: 31950979 Intervention aside, is hydrocortisone q6hrs standard of care now? I thought ADRENAL was a negative study@PaulBerglMD@iBookCC@critcareguys@cathryntlee@WF_Parkerpic.twitter.com/XTC5apZJQD
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Mike Putman proslijedio/la je Tweet
Support public funding for research. Donate to the Rheumatology Research Foundation
@RheumResearchHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Curious to hear what people think: “Pharmaceutical companies should be able to fund, help write, and approve the final draft of clinical practice guidelines”
@RheumNow@LCalabreseDO@psufka@DrBhana@BekRx@Drbeckyg@uptoTate@DanielHSolomon@DamanLangguth@philipcrobinsonPrikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
NEW Guidelines for SSc-ILD
@TheLancetRheum 1. HRCT at dx
2. Lovely flowchart!
3. Nintedanib gets its own table?
4. FUNDED by PHARMA?
5. WRITING HELP from PHARMA?
Apparently practice guidelines are now paid for and co-authored by pharma...
https://www.thelancet.com/action/showPdf?pii=S2665-9913%2819%2930144-4 …pic.twitter.com/xyMgtoIB8s
Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
2020 Medscape Physician Survey: https://www.medscape.com/slideshow/2018-lifestyle-happiness-6009320 … Per usual, rheum did well w/number needed to specialize (NNS) ~ 8 vs less happy ones ;) Lots of selection bias, responder bias, etc but I’ll admit I looked at this when choosing a path! Thanks
@uptoTate for the poll!pic.twitter.com/32CmCCBt3f
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Mike Putman proslijedio/la je Tweet
Rheum4Debate is back!
@anisha_dua and@sarahfantus will debate this motion: "In MTX non-responders with RA, triple therapy (adding HCQ & SSZ) should be first line" Vote the pre-debate poll NOW to have you voice heard! Podcast lands next Thursday :)Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Rheum4Debate is back!
@anisha_dua and@sarahfantus will debate this motion: "In MTX non-responders with RA, triple therapy (adding HCQ & SSZ) should be first line" Vote the pre-debate poll NOW to have you voice heard! Podcast lands next Thursday :)Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Thoroughly enjoyed
@EpiEllie on DAGs in recent@casualinfer podcast Reminded me of my favorite one of all time, where@DrCMcMaster managed to fit the entirety of nutritional epi into one DAG https://en.m.wikipedia.org/wiki/Directed_acyclic_graph …pic.twitter.com/YMi5WED90p
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2020 ACR Guidelines for OA in A&R this week Generally recommend: exercise, wt loss, CMC orthosis, NSAIDS, CSI Strongly against: TENS, glucosamine, chondroitin, PRP, stem cells, all DMARDS NGFi (promising?) and chiro (less so) missed the party Nice job
@Tuhina_Neogi et al!pic.twitter.com/5qK1QFgrf2
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Fun to hear an old favorite (
@VPrasadMDMPH) put out a podcast with a new favorite (@EpiEllie) Listen to both and checkout the Casual Inference podcast!!@casualinferhttps://overcast.fm/+ORIA6Ei54Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
#tbt 2013 RACAT, triple tx vs TNF in MTX resistant RA, PMID 23755969 Typically interpreted "Triple Tx and TNF have equal efficacy" Re-read recently & noted significant differences favoring ETN for remission: DAS28<2.6 (NNT~11) & ACR70 (NNT~9) Wondering if we have this right...pic.twitter.com/papHT7OZ3u
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Someone’s mother has four sons. North, South and East. What is the name of the fourth son. Private message me the name of the fourth son. If you lose, you have to repost. I lost to
@DrPujaMehta1Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi
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