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Thomas Dayspring proslijedio/la je Tweet
Does early
#heartdisease run in your family? What about#cholesterol? Learn more: http://www.theFHFoundation.org/heartdisase#HeartMonth
#KnowFHpic.twitter.com/OgxCj6UC5u
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Trial planned to help settle the debate over using Keto Diet with T2Dhttps://khn.org/news/veterans-keto-diet-va-test-to-treat-type-2-diabetes-skeptics-raise-red-flags/ …
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Not good for lipid/CV care: Insured adults have been visiting PCPs less often & nearly 1/2 had no PCP visits in a given year by 2016. This decline may be explained by decreased/perceived visit needs, $$ deterrents & use of alternative care. http://ow.ly/dCkJ50ycxzx
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NOT REALLY DEBATABLE - For each 39mg/dL (1mmol/L) LDLc lowering, the RR of MACE is independent of the starting LDLc or presence of DM or CKD. Pts at lower CV risk & younger age might have a similar relative reduction in risk with LDLc lowering therapieshttp://ow.ly/BRjL50ybTQt
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Thomas Dayspring proslijedio/la je Tweet
The latest LipidDoc's Daily is out !! https://paper.li/lipiddoc/1397423108?edition_id=280f9b10-4654-11ea-9ec3-0cc47a0d164b … Thanks to
@ArsenaultBenoit@DrMarthaGulati@ASPCardio#hearthealth#cvdHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Thomas Dayspring proslijedio/la je Tweet
GRADE guidelines 27: how to calculate absolute effects for time-to-event outcomes in summary of findings tables and Evidence Profileshttps://www.jclinepi.com/article/S0895-4356(19)30422-6/fulltext#.XjPZZWOuM4U.twitter …
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On top of all the nightmare issues raised by
@KatherineEban re generics, now read about the issues pharmacists dispensing the drugs facehttps://www.nytimes.com/2020/01/31/health/pharmacists-medication-errors.html?smid=nytcore-ios-share …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
A strikingly high proportion of FH subjects (40%) lacked mutations in known culprit genes. Mutation(-) pts were older (mean 49 vs 57), & had more African Americans (1% vs 12.5%), more HTN (21% vs 46%) & inc TG (median 86 mg/dL vs 122 mg/dL) levels.https://academic.oup.com/jes/article/4/1/bvz015/5645712 …
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More evidence there is little to worry about when appropriately reducing LDL metrics for CV benefit.https://twitter.com/AviBittMD/status/1222981093273501696 …
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CLICK TO ENLARGE - With respect to choelsterol homeostasis: a good place to start your learning curve is serious study of the membrane sterol infux/export transporters at gut/enterocyte and hepatobiliary interfaces -pic.twitter.com/8xNaDlztsF
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Thomas Dayspring proslijedio/la je Tweet
Recognition & Treatment of
#HoFH by Primary Care Physicians: Survey from@NationalLipid shows need for more education in recognizing & treating HoFH, greater access to lipid specialists & LDL-apheresis https://rdcu.be/b0ZqX@lipidboard@TheFHFoundation#KnowFH@NLAFoundationpic.twitter.com/Ria7OeouQN
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CLICK TO ENLARGE - To understand sterol (meaning cholesterol and xenosteols) absorption/homeostasis you will need to maste the functions of several hepatic and enterocytic receptorspic.twitter.com/FvAEuqb6tg
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CLICK TO ENLARGE - Intestinal Cholesterol Absorptionpic.twitter.com/Itl6cKvhzk
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Thomas Dayspring proslijedio/la je Tweet
New triglyceride-lowering therapy alert! A dual apoC-II mimetic–apoC-III antagonist peptide promotes lipolysis and lowers plasma triglycerides
@ScienceTMhttps://stm.sciencemag.org/content/12/528/eaaw7905 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Hypothesis: With respect to eggs and cholesterol homeostasis - Daily intake might differently affect sterol hyper-absorbers compared to those with normo-absorption or hypo-absorbers: related to gain or or loss of function of sterol influx/efflux transporters (NPC1L1 or ABCG5/G8)
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If needed beyond lifestyle to achieve desired (and individualized) HgbA1c goals the FDA has approved : a three in one therapy (called Trijardy XR) for management of T2D. Added to metformin is an SGLT2i (empaglifozin) & a DPP4i (linagliptin)https://www.mdedge.com/endocrinology/article/216254/diabetes/fda-okays-triple-combo-pill-type-2-diabetes …
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No association of Egg Intake (≥7 egg/wk compared with <1 egg/wk intake) with blood lipids, CVD, and mortality in 177,000 People in 50 Countrieshttp://ow.ly/lf1q50y7AeV
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Clinical trials of high doses of vitamin D are not finding the benefits that some advocates had promoted and are even hinting at some adverse effects.https://endocrinenews.endocrine.org/vitamin-d-when-enough-is-enough/ …
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CAD & its consequences remain the leading causes of premature death and lifelong disability in most countries: Read - Stable ischemic heart disease: how to keep it that way http://ow.ly/lYo650y6pY4
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Listen to the "Codfather" - Dr Bill Harris briefly explain why all should get their Omega-3 Index checked. The test is a steady state, erythrocyte phospholipid-omega 3 metric which should not be confused with the variable plasma (serum) omega 3 testhttps://www.youtube.com/watch?v=fEvD4kIyELw&feature=youtu.be …
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