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DrEricDing's profile
Eric Feigl-Ding
Eric Feigl-Ding
Eric Feigl-Ding
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@DrEricDing

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Eric Feigl-DingVerified account

@DrEricDing

Epidemiologist & health economist. Senior Fellow @FAScientists. Former 16 years @Harvard. @JohnsHopkins alum. COVID updates since Jan '20: http://nym.ag/3olszuo 

Washington DC & Virginia
fas.org/expert/eric-fe…
Joined January 2009

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    1. Eric Feigl-Ding‏Verified account @DrEricDing 25 Jan 2021

      A NEW HOPE: 27x more effective than Remdesivir against #COVID19 in lab study –Aplidin is a drug derived from a marine sea squirt found only in waters off 🇪🇸 island of Ibiza. A cancer drug for multiple myeloma, it’s showing COVID success in lab studies. 🧵 https://www.jsonline.com/story/news/2021/01/25/international-team-finds-new-more-effective-drug-treat-covid-19/6673529002/ …pic.twitter.com/wPykAWKedf

      233 replies 3,086 retweets 8,788 likes
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    2. Eric Feigl-Ding‏Verified account @DrEricDing 25 Jan 2021

      2) International team of scientists identify new treatment for COVID-19 that appears to be far more effective than current drugs. https://www.jsonline.com/story/news/2021/01/25/international-team-finds-new-more-effective-drug-treat-covid-19/6673529002/ … A related preprint says that tests have shown the drug is equally effective against #b117 variant too!

      16 replies 298 retweets 1,043 likes
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    3. Eric Feigl-Ding‏Verified account @DrEricDing 25 Jan 2021

      3) Aplidin, already approved in Australia for treating multiple myeloma, has been developed as a potential COVID-19 treatment by the Spanish drug company PharMar.  The drug was identified as a potential treatment after scientists at UCSF tried an unconventional approach...

      7 replies 150 retweets 707 likes
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    4. Eric Feigl-Ding‏Verified account @DrEricDing 25 Jan 2021

      4) Instead of randomly testing vast libraries of existing drugs or targeting key proteins in the virus, the UCSF team focused on human proteins needed by the virus. The scientists then looked for existing drugs that would prevent #SARSCoV2 from hijacking those human proteins.

      4 replies 136 retweets 736 likes
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    5. Eric Feigl-Ding‏Verified account @DrEricDing 25 Jan 2021

      5) “This was data driven instead of just randomly screening drugs," stressed Nevan Krogan, one of three co-leaders of the new study in Science and director of the Quantitative Biosciences Institute at the University of California, San Francisco.

      2 replies 97 retweets 599 likes
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      Eric Feigl-Ding‏Verified account @DrEricDing 25 Jan 2021

      6) “Krogan said focusing on human, rather the viral, proteins, offered a powerful advantage in the fight against the new coronavirus. ➡️"If you target a human protein that the virus needs," he said, "the virus will **never mutate away** from being reliant on that human protein."

      4:45 PM - 25 Jan 2021
      • 117 Retweets
      • 621 Likes
      • Susan Todd 😷💉 Katherine Schlag Diana 🇮🇹 😷💉 BobLobLawsLawOffice Mary J ONeil An antelope @🏡 😷🇨🇦💉💉💉 Steve Sheryl Brown MD CCFP Norbert Styles
      1 reply 117 retweets 621 likes
        1. New conversation
        2. Eric Feigl-Ding‏Verified account @DrEricDing 25 Jan 2021

          7) Aplidin, also known as Plitidepsin, has gone through a Phase II clinical trial against COVID-19 and is now awaiting the start of Phase III testing. It comes from sea squirts, marine creatures that look like plants and have tubular openings allowing them to draw water.

          11 replies 125 retweets 643 likes
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        3. Eric Feigl-Ding‏Verified account @DrEricDing 25 Jan 2021

          8) also to be clear— this is not some small minor study — it was published in SCIENCE!!! One of the top science journals in the world.https://science.sciencemag.org/content/early/2021/01/22/science.abf4058 …

          11 replies 196 retweets 836 likes
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        4. Eric Feigl-Ding‏Verified account @DrEricDing 25 Jan 2021

          9) And the 27x greater potency of #Aplidin against Remdesivir claim against #SARSCoV2? It’s backed up by evidence in-vitro in the Science article itself!pic.twitter.com/FAYOdGeerq

          7 replies 119 retweets 631 likes
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        5. Eric Feigl-Ding‏Verified account @DrEricDing 25 Jan 2021

          10) in mice, It also found reduction of #sarscov2 viral replication by 2 orders of magnitude in lungs too.pic.twitter.com/7i7s65qBPZ

          30 replies 83 retweets 545 likes
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        6. End of conversation

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