“Where did the
come from?” is one of the most asked questions. First, I don’t like unsupported conspiracy theories, but it’s a lingering question. @sciencemagazine examined this based on Lancet article. Nobody knows, but seafood market isn’t whole storyhttps://www.sciencemag.org/news/2020/01/wuhan-seafood-market-may-not-be-source-novel-virus-spreading-globally …
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11. Dubbing this the [GENETIC THREAD]
thread, let’s delve back into the genetic similarities of the new
with SARS and bat #coronaviruses. Study in Lancet says ~88% related to closest bat coronavirus, 79% to SARS (which is more than humans-elephants) https://marlin-prod.literatumonline.com/pb-assets/Lancet/pdfs/S0140673620302518.pdf …pic.twitter.com/2568DtbsoJ
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12. ...As you can see, the new nCOV is a branch off the bat coronavirus subgenus. It is too distant from SARS (79%) or MERS (only 50% related)pic.twitter.com/A3nxtwt7Jh
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13. For the most part, the new
#coronavirus shares 87-88% overlap with bat coronavirus. But there are parts of it like the “S” gene
region where I drops to ~70%, and even 68% in lowest point. But other gene regions share
consensus as high as 95%.pic.twitter.com/XrIQOfgSOQ
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14. What is in the “S”
region of the #coronavirus? According to the Lancet piece (link
above), it encodes the virus envelop spike protein of the
for binding receptors of host cells - “crucial for host tropism” — which basically identifies how to target
host tissue.pic.twitter.com/rtqjDrtRgw
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15. One source or many sources? The mutation rate suggests the 2019-nCoV came from just one recent source in single jump (as opposed to several mutation sources). This doesn’t mean much other than it wasn’t several strains that started outbreak. Don’t over-interpret. Just FYI.pic.twitter.com/utEN7O4krg
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You need to be careful.
Thanks. Twitter will use this to make your timeline better. UndoUndo
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Yea the authors of the paper are legit.
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This is from the 2016 paper out of UNC where they bio-engineered another bat coronavirus and made it incredibly virulentpic.twitter.com/vi69qHIotM
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But how could they know the effect upon humans without it being tested on humans? There is only one place in the world where this could happen.. As discussed here.. https://youtu.be/tX859E6hAN4?t=524 …
#coronavirus
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” is often heard, but it’s trickier. The 
