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Congrats! A wonderful vision of Engineered Living Materials and its potential impact for the future by Neel Joshi and
@wyssinstitute team.https://twitter.com/jeloshine/status/1224757961689571329 …
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Don Ingber proslijedio/la je Tweet
RT
@newsbeagle: Link together 10 organs-on-chips and what do you get? A body-on-a-chip, sorta.@Scudellari reports on the@wyssinstitute's results from a@DARPA challenge, which could reduce drug testing on humans and animals: https://spectrum.ieee.org/the-human-os/biomedical/devices/bodyonchip-darpa-challenge …pic.twitter.com/Ju8nWNX9lj
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Anyone interested in our
@NatureProtocols paper from@wyssinstitute on the robotic smoking Lung Chip can find it at https://rdcu.be/b08Vk@KambezBenamhttps://twitter.com/BioMed_21/status/1217463993188724737 …
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A fox in a coyote outfit perhaps?https://twitter.com/DonIngber/status/1224702728875757568 …
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If a fox and a badger can get along when it's clear that working together represents the only way out, why can't republicans and democrats do the same?https://twitter.com/PeccaryNotPig/status/1224515892282740737 …
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We have also replicated immune responses in numerous past articles on Organ Chips.https://twitter.com/JishnuSenGupta/status/1222889657379278848 …
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In a past article with
@emulateinc, we flowed whole human blood flowing through endothelium-lined vascular channels of an Organ Chip and replicated thrombotic complications of drug that caused deaths due to pulmonary thrombosis in humans, but not animals.https://pubmed.ncbi.nlm.nih.gov/29484632-organ-on-chip-recapitulates-thrombosis-induced-by-an-anti-cd154-monoclonal-antibody-translational-potential-of-advanced-microengineered-systems/?from_term=ingber+and+jain&from_sort=date&from_pos=2 …https://twitter.com/JishnuSenGupta/status/1222889657379278848 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Please read our 3 articles in
@natBME, on human Body-on-Chips & our Bone Marrow Chip where we recreate clinical drug PK profiles with flow and observe clinical regimen-specific toxicities: https://rdcu.be/b0OZX https://rdcu.be/b0O1z https://rdcu.be/b0OZF https://twitter.com/JishnuSenGupta/status/1222568013217460224 …pic.twitter.com/NHx4GIm5wU
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This is NOT a high throughput assay. This quantitatively predicts human drug PK parameters (t1/2, Cmax) by adminstering drugs orally (via lumen of Intestine Chip) or iv (via endothelium-lined vascular channels) by measuring drug levels throughout and using computational modeling.https://twitter.com/JishnuSenGupta/status/1222568013217460224 …
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Don Ingber proslijedio/la je Tweet
The Magnum opus of organ linking !! Delighted to have been part of this monumental achievement. Spectacular example of interdisciplinary teamwork with colleagues
@wyssinstitute@Harvardhttps://twitter.com/natbme/status/1221828696337780736 …
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Don Ingber proslijedio/la je Tweet
Organ on a Chip Shop opens for business at Science Museum Lates tonight!pic.twitter.com/KCzK7R6YYu
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Don Ingber proslijedio/la je Tweet
A great example of collaboration at the Wyss.https://twitter.com/drmichaellevin/status/1222311463433506816 …
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Don Ingber proslijedio/la je Tweet
#Bonemarrow#organchips provide new research directions for Shwachman-Diamond syndrome: great collaboration between Akiko Shimamura@DFBC_PedCare and@wyssinstitute:http://discoveries.childrenshospital.org/sds-bone-marrow-organ-on-a-chip/ …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Don Ingber proslijedio/la je Tweet
Two recent publications in
@ScienceTM and@natBME, to which we were authors alongside@emulateinc and@wyssinstitute, outline the critical importance of more predictive and human-relevant models in drug discovery. Read more here: http://bit.ly/2O3S3cW .pic.twitter.com/Jegl2URE2Y
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Don Ingber proslijedio/la je Tweet
Do you want to receive monthly email updates with Wyss news? You're in luck! The Wyss is introducing an email digest that will include all of the latest information from inside the Institute. Sign up now, before the first one comes out. https://share.hsforms.com/1ffJtij8JT7uTx0mIs6VuaQ16cx0 …pic.twitter.com/KGUrvnnpN0
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This is a great article reviewing recent developments in Mechanobiokogy that demonstrate the importance of physical forces for tissue morphogenesis and organ formation.https://twitter.com/wyssinstitute/status/1222253414991581184 …
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We are very excited about this new Bone Marrow Chip because for the first time we mimic drug responses to clinically relevant exposure (PK) profiles, and we also created a patient-specific model of a rare genetic disorder and learned something new about mechanism.https://twitter.com/wyssinstitute/status/1221825680071020544 …
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Here's an overview of how we developed the Human Body-on-Chips through a monumental, interdisciplinary, collaborative effort
@wyssinstitute over the past 7 years. https://bioengineeringcommunity.nature.com/users/255947-donald-e-ingber-md-phd/posts/57815-predicting-human-drug-pharmacokinetics-and-pharmacodynamics-using-human-body-on-chips-technology …pic.twitter.com/3WBDPsxug8
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