Occasional reminder that I'm on Post.news as . I'm watching other alternatives (Spoutible, etc.) as they launch in the coming weeks/months.
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Derek Lowe
@Dereklowe
Drug discovery chemist and blogger
Note: all opinions, choices of topic, etc. are strictly my own – I don’t in any way speak for my employer (or anyone else).
Derek Lowe’s Tweets
Feedly has been working flawlessly for me for years (aside from a slight hiccup during site upgrade). I have the feed as: science.org/blogs/pipeline
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It is with profound sadness that I move myself up in the ranking of “my favorite Dereks on twitter” as #1 is leaving
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I won’t bury the lede here: I’m leaving Twitter, as of later today. (1/)
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It's probably only a question of time before I leave here as well. This kind of rhetoric makes me feel unsafe as an openly queer person. Which is unfortunate, because I owe so much to the science twitter community.
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Now he’s accused recently-resigned Twitter staffers of being pedophiles (which sounds familiar after his 2018 Thailand cave-diver fiasco) and tweeted out “Prosecute Fauci” as an idiotic pronoun joke. Someone will get hurt as this continues. (4/)
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I've been thinking the same thing. It's fun to interact with the community here, but I'm not sure the benefits of being here outweigh the risks to public health by spending any time here.
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I won’t bury the lede here: I’m leaving Twitter, as of later today. (1/)
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The bearded one has left the building.
Have been trading thoughts with Derek for, what, fifteen years? A real loss and a sign of the toxicity journalists can see in our DMs.
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I won’t bury the lede here: I’m leaving Twitter, as of later today. (1/)
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My plan is to try to make a home at Post.news, and we’ll see how that plays out. If not there, somewhere else after that. Good luck to everyone!
post.news/dereklowe
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I’ll leave my account up for reference and to keep anyone from causing trouble by re-using my name. But I’m not making content for Elon. I will not be checking Twitter after today, so DMs will not be a good way to contact me. (12/)
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The blog continues at science.org/blogs/pipeline, and I can always be reached at derekb.lowe@gmail.com. I’m at Post.news, u/dblowe on Reddit, and I may yet try out Mastodon as well. (11/)
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If I have any credibility to lend or usefulness to add, I don’t want to give it to what Twitter is becoming. What that might be is “bankrupt” at the rate things are going, honestly. Anyway, I’ll miss a lot of people here, but I can still be found! (10/)
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People have advised just blocking/muting him and others, and that does improve the experience here. But closing my eyes doesn’t make the rising levels of bullshit disappear. In the end, I don’t want to give this platform any more time and energy. (9/)
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The levels of misinformation here (medical and otherwise) are increasing, and the site now doesn’t even attempt to do anything about it. Quite the opposite. Its owner is giggling while he cheers the stuff on. Why not? Outrage = clicks and engagement. (7/)
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There have always been folks like that on this site, of course. But I used to take time to report their tweets, and the worst of them would get banned. Now Twitter’s owner is stroking their fur and feeding them little treats. (6/)
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He’s reinstating, replying to, encouraging, and agreeing with an assortment of other trolls, racists, anti-Semites, anti-LBGTQ, Qanon enthusiasts, etc. These are his people. That’s his vision for Twitter. We should believe him when he shows us. (5/)
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Now he’s accused recently-resigned Twitter staffers of being pedophiles (which sounds familiar after his 2018 Thailand cave-diver fiasco) and tweeted out “Prosecute Fauci” as an idiotic pronoun joke. Someone will get hurt as this continues. (4/)
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It is, of course, what has done to the place, is doing, and will surely continue to do. I’ve seen enough. Weird business decisions aside, he’s an erratic attention-seeking troll, and he (like any such person) is just getting worse with time. (3/)
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I am very unhappy about this. I’ve met a lot of great people on this platform and it’s been a valuable source of news and communication over the years. I’ll miss it terribly, and I've been debating this for weeks. But I can’t stay. (2/)
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I won’t bury the lede here: I’m leaving Twitter, as of later today. (1/)
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Replying to
Remember when we all thought it was bots that were the problem? Yeah it wasn't that.
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A lot of people are having this conversation with themselves:
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I’m really struggling with whether I should remain here, given the CEO is hell-bent on turning this site into a disinformation machine for persecuting scientists & marginalized groups. There’s value in pushback but just using the platform creates value for the guy in charge. So:
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SCOOP: Net energy gain in a fusion reaction has been a holy grail in science for decades. Now I’m told US scientists have done it. A massive breakthrough with revolutionary potential for clean power. US Energy Secretary to hold a press conference Tuesday
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Simple to resolve by the Power of Twitter. please can you tell us what the 95% confidence intervals were for this? Asking for myself and a lot of friends.
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Replying to
For me Derek Lowe's blog convinced me that medicinal chemists are the smartest people alive.
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Elon Musk is a monster. Full stop. He’s tweeted out “prosecute/Fauci..” This is a billionaire amping up millions to go after an federal official. 1/
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When the Nobel Peace Prize is awarded today, Ales Bialiatski will be in his cell, awaiting trial as he has for 448 days. He should be in Oslo, receiving his Peace Prize for promoting the right to criticize power and protect the fundamental rights of citizens. (1/3)
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How not to present a survival analysis in the world's preeminent medical journal when reporting on a new treatment for #Alzheimers
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There's a parallel universe where clean-shaven Derek is an extraordinarily successful columnist for American Trucker magazine, and hosts a show every Friday on CB channel 17 at 7 PM Central.
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Replying to @Chemjobber
Organic synthetic writeups in SEO-optimized style would push me over closer to a life on the road, driving the big rigs. Or perhaps a move to Montana, farming wolverines or something.
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Tested pos for covid today. Called my provider and asked for a telemed appt and Paxlovid. I was offered a choice between Monday (too late for Paxlovid) or--I am not making this up--January 9th.
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Can't believe they missed us off this list AGAIN.
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We should stop describing proteins as being in "the unfolded state", because there isn't just one of those. We have enough "things that aren't things" already:
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Subsequent development of #LongCovid detected by gene expression during acute infection. Two different patterns related to antibody production to spike protein
nature.com/articles/s4159
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What the people of Iran are up against: a death sentence because protest against the regime is moharebeh, “waging war against God”.
And hundreds of others have been shot or beaten to death without even this legal fiction. . .
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Iran has executed protester Mohsen Shekari after convicting him of waging war against God for allegedly injuring a Basij member and blocking a street. Shekari is the first protester to be hanged since antiestablishment protests erupted in September.
#محسن_شکاری #اعدام_نکنید
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Thanks, just watched the occultation in real time through my little Celestron scope; probably the coolest thing I've seen through it!
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Thread on Valisure, the company that helped set off the controversy over nitroso contamination in pharmaceuticals:
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I'm not an analytical chemist, so I don't have much to say about FDA's critique that Valisure failed to validate their GC/MS method for NDMA detection raps.org/news-and-artic
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FDA scolds company that raised red flags over impurities in many widely used medicines
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Replying to
Don't forget tonight's occultation of Mars by the Moon!
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a YouTube comment about the way AI destroyed the field of translation years ago
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