Derek Croote

@DerekCroote

CTO of IgGenix. sufferer & scientist. previously PhD

Bay Area, CA
Vrijeme pridruživanja: ožujak 2018.

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  1. Prikvačeni tweet
    14. pro 2018.

    I am excited to share our work on single B cells that produce IgE antibodies responsible for : “High-affinity allergen-specific human antibodies cloned from single IgE B cell transcriptomes” - (thread: 1/7)

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  2. 31. sij

    Remember, you can balance your centrifuge IFF both the number of tubes K and open positions N-K can be written as sums of prime factors of the total number of positions N 🙃

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  3. 12. ruj 2019.

    Bad drivers can take out the whole field (anti-vaxxers). (10/10)

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  4. 12. ruj 2019.

    Warming up the car is necessary at the start of the race (passive immunity from mother to newborn). (9/10)

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  5. 12. ruj 2019.

    Adaptations must be made to the environment, like wet tyres in the rain (vaccines before travel). (8/10)

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  6. 12. ruj 2019.

    During an uncontrolled slide from excessive braking, an otherwise harmless foam barrier can severely damage the car (infection while immunocompromised). (7/10)

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  7. 12. ruj 2019.

    Too aggressive and components can wear excessively, break, or explode (autoimmunity). (6/10)

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  8. 12. ruj 2019.

    A fresh set of tyres can be salvage a losing strategy, but carries risk (hematopoietic stem cell transplant). (5/10)

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  9. 12. ruj 2019.

    Drivers take familiar turns faster (immunological memory provides defense against previously observed pathogens). (4/10)

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  10. 12. ruj 2019.

    There is a single driver, but the backing of an entire specialized team (innate and adaptive immune cells, antibodies, cytokines, antimicrobial peptides...). (3/10)

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  11. 12. ruj 2019.

    The car is exquisitely engineered and being continuously improved (millions of years of co-evolution between pathogens and the immune system). (2/10)

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  12. 12. ruj 2019.

    The immune system as motorsport. A thread 🤓 and public service reminder 💉 (1/10)

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  13. proslijedio/la je Tweet
    4. ruj 2019.

    New work from CBB student Julian Zhou leveraging data from and to show that Ig H chains are sufficient to determine most B cell clonal relationships. <20% of clusters express inconsistent L chains. .

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  14. 5. kol 2019.

    I am forced to read food labels with phrases like "may contain [allergen]" every day. We assessed whether foods actually contained these allergens using mass spectrometry and a new computational approach. I'm excited that this work is now out in !

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  15. proslijedio/la je Tweet
    31. srp 2019.

    Frustrated when you see that a food item "may contain" an allergen? Reducing matrix interference in food analysis can give you a more definitive answer

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  16. 22. srp 2019.

    New preprint out today from fellow Quake lab member Felix Horns: pairing single-cell transcriptomics with antibody characterization reveals an anti-influenza memory B cell vaccine response, but also bystander activation:

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  17. 9. srp 2019.

    How many corporate leaders would, in the face of failed diplomacy, assemble a special operations team to free their imprisoned employees from a hostile nation? Ross Perot did that, thrillingly detailed in On Wings of Eagles by

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  18. 14. lip 2019.

    Excellent resource for therapeutic antibody sequences and structures

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  19. 12. lip 2019.
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  20. 11. lip 2019.

    For current (or future) Stanford PhD students: I've created an example LaTeX thesis based on the existing Stanford style guide. Hopefully this can save you time on the minutiae of thesis writing.

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  21. 9. lip 2019.

    ❄️☕ Improving cold brew coffee extraction with a repurposed 1980 chemistry stir plate. ✅ Complete grounds immersion ✅ Accelerated brewing ✅ Mad scientist appeal

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