So the placebo-effect as part of the total effect of a antidepressant, is 90%?
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This possibility could only be tested in trials where patients are administered the drugs unwittingly. Has been done with pain medicine.
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Did the increasing awareness of antidepressants affect subject expectations? Is there a generational shift?
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most direct test of expectations hypothesis I know of (comparing patients that suffer SSRI side-effects vs. not) is negative https://www.nature.com/articles/mp2017147.pdf …
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