Dean Pontius

@DeanPontius

Molecular medicine PhD student /. alumn. Strava user when I remember.

Cleveland, OH
Vrijeme pridruživanja: lipanj 2017.

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  1. proslijedio/la je Tweet
    9. pro 2019.

    An investigation of oncogenes amplified on circular extrachromosomal DNA and other forms of regulatory rewiring to promote cancer growth

    Functional Enhancers Shape Extrachromosomal Oncogene Amplifications. Morton et al. (2019) Cell
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  2. proslijedio/la je Tweet
    27. stu 2019.

    Here’s a link to read and download for those without a subscription. Check it out!

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  3. proslijedio/la je Tweet
    21. stu 2019.

    1/ So excited to have our work joint with the Rich lab lead by published in Cell today: “Functional enhancers shape extrachromosomal oncogene amplifications”. below

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  4. proslijedio/la je Tweet
    17. lis 2019.

    Watson is opening for the single-cell show on Friday 9am at grand ballroom c. Come check it out and Spread the wordS thanks

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  5. proslijedio/la je Tweet
    9. ruj 2019.

    Our latest is out! Awesome collaboration with George Lab . We developed an approach to screen for drugs that inhibit osteosarcoma cells from growing in the lung, where they metastasize. CDK12 inhibitors are especially effective.

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    23. kol 2019.

    Rigorous Hi-C bias corrrection (HiCorr) can significantly improve the sensitivity and robustness of Hi-C loop calling at sub-TAD level, especially enhancer-promoter interactions.

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  7. 9. lip 2019.

    Perfect weather for the race to 5k . Can’t lie, very jealous of ’s closeup with Zumi

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  8. proslijedio/la je Tweet
    27. tra 2019.

    Us: a bunch of fun, passionate folks working in the interstices of math, physics, medicine & evolutionary bio on problems plaguing humanity ( & ) You: about to finish college, looking for a gap year/years before applying to MD, PhD or MD/PhD programs.

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  9. proslijedio/la je Tweet
    14. ožu 2019.

    Our work on disease associated single-cell trajectory in pancreatic beta cell combined with genome-wide CRISPR screen is out ! Great collaboration with Zhou. Check our RePACT for disease trajectory analysis

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    14. ožu 2019.
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  11. 9. ožu 2019.

    Racing to in the lab and at Edgewater park June 9th. Join the race or donate here

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  12. proslijedio/la je Tweet
    7. ožu 2019.

    Thrilled to share some new work out of our lab we just posted on , would be interested in hearing some feedback! New role for asymmetric cell division in glioblastoma cancer stem cells to increase therapeutic resistance

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    Super excited to be hosting PhD candidates for our Molecular Medicine Program Interview days! RETC has pack schedule to highlight our outstanding .

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  14. proslijedio/la je Tweet
    13. velj 2019.

    Check out our lab's latest paper on MMR-mutations as enhancer activators in colon cancer. Couldn't be more pleased with their review process. Special congrats to lead author and MD-PhD student Stevephen Hung. As always, feedback is welcome.

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    Just a tiny bit of magic* to simplify your day: (*magic, code, whatever)

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  16. proslijedio/la je Tweet
    22. lis 2018.
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  17. proslijedio/la je Tweet
    7. ruj 2018.

    Mismatch-repair signature mutations activate gene enhancers across colorectal cancer epigenomes

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  18. proslijedio/la je Tweet
    7. kol 2018.

    Here's the Real Story about the Impossible Burger

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  19. proslijedio/la je Tweet
    5. kol 2018.

    Scacheri Lab at the finish of the ⁦⁩ 5k

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  20. proslijedio/la je Tweet
    2. kol 2018.

    Thrilled to have two papers from our lab & finally out today, our single cell atlas of mouse chromatin accessibility () led by and Cicero algorithm for linking reg. elements () led by

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