Just eyeballing it it seems clearly more impactful (over the medium term) to give 20-40yo their first COVID shot to slow transmission of the virus, rather than give 40-65yo their second shot, which only very incrementally lowers their risk of death or transmitting the virus.
the wildcard here is if just one shot creates an environment for supermutation in, say immunocompromised people, like was theorized to happen for the kent variant. such people should still get a 2nd shot
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Having more people infected by the virus also means more mutations to evade the immune system. :/
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indeed! the radical proposal I am in favor of is MRNA manufacturing appropriation for some reasonable # of $ billions! we should have scaled this up not by a factor of 2x, but 10x!
End of conversation
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