the point i was making here is that it was a variant of that flu in the 2nd / 3rd wave that started being really effective in taking down even strong immune systems
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50 million died! it was nearly 3% of the world population! a third of humanity was infected. almost all cases of influenza subsequently have been caused by descendants of the 1918 virus. it isn't true that it's gone away, even if our collective immune defences mitigate itpic.twitter.com/74Ul1H8Bha
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you've missed my point, which is that we haven't seen the end of this virus in terms of severity of disease, or lethality. the spanish flu became >25x more deadly, mutating in the squalid conditions of the trenches of europe during ww1, in a young population. what can happen here
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Replying to @MatHeller1 @MLevitt_NP2013 and
in the case of this virus, variants that increase the absolute amount of viral particles produced, or more presented spike protein, provides a straightforward mechanism for the virus to get more infectious & more severe. killing the host at the end is a bearable cost for it
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that very specifically *is* what’s happening in the b.1.1.7 variant, and it also happened with the d614g variant (though it was not significantly more severe)
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