This is a very good post In California ~2% of the population has been vaccinated, but we have enough vaccine for ~9% of the population. If done in the elderly as fast as possible - no red tape! - deaths would drop by > half(!!!) We have the vaccine to do this _today_, but aren't https://twitter.com/eladgil/status/1349802287355490304 …
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Also, kudos to
@Padres@SupFletcher@UCSDHealth@SanDiegoCounty and@CityOfSanDiego for this - great stuff, and noted!pic.twitter.com/Qr8w2J0doL
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Michael Nielsen Retweeted Kim-Mai Cutler
A good caveat from
@kimmaicutler: https://twitter.com/kimmaicutler/status/1349836415966670849 … My understanding is: (a) both Biden & Trump admins now advise just-in-time, not holding back for second dose; & (b) 1 dose still poorly understood, but at least some (incomplete!) data suggests > 80% protection.Michael Nielsen added,
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Replying to @michael_nielsen @kimmaicutler
fwiw, i don’t think the single dose approach is worth the additional risk of providing and evolutionary environment for the virus to achieve immune escape
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Arguably wouldn't that happen regardless in other countries that go with the single dose approach or administer the less effective non-mRNA vaccines?
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it's possible, even possible that that has already happened, or that the brazilian variant's immune escape resistance is what's partially or wholly responsible for the 50% effectiveness of sinovac (down from only 80%). data from israel shows 33% eff. after 1st dose, not enough
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