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DanielleFong's profile
𝓓𝑎𝑛𝑖𝑒𝑙𝑙𝑒 𝓕𝑜𝑛𝑔, 𝕖𝕩-𝕡𝕣𝕠𝕕𝕚𝕘𝕪
𝓓𝑎𝑛𝑖𝑒𝑙𝑙𝑒 𝓕𝑜𝑛𝑔, 𝕖𝕩-𝕡𝕣𝕠𝕕𝕚𝕘𝕪
𝓓𝑎𝑛𝑖𝑒𝑙𝑙𝑒 𝓕𝑜𝑛𝑔, 𝕖𝕩-𝕡𝕣𝕠𝕕𝕚𝕘𝕪
@DanielleFong

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𝓓𝑎𝑛𝑖𝑒𝑙𝑙𝑒 𝓕𝑜𝑛𝑔, 𝕖𝕩-𝕡𝕣𝕠𝕕𝕚𝕘𝕪

@DanielleFong

𝔞 𝔟𝔩𝔞𝕤𝔱 𝔣𝔯𝔬𝔪 𝔱𝕙𝖊 𝔭𝔞𝔰𝔱 𝕝𝕖𝕧𝕖𝕝 𝟛𝟚 𝕤𝕠𝕣𝕔𝕖𝕣𝕖𝕤𝕤, 𝕙𝕒𝕣𝕕𝕔𝕠𝕣𝕖 𝕞𝕠𝕕𝕖

.earth  🌎
daniellefong.com
Joined February 2008

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    1. David Sinclair, PhD‏Verified account @davidasinclair May 11
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      Memory improvements anyone? By the third month, it was clear that treated rats remembered the test maze much better than the untreated ones. 14/n

      3 replies 10 retweets 223 likes
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    2. David Sinclair, PhD‏Verified account @davidasinclair May 11
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      The brain was an exception in terms of age-reversal, where the age reduction was significant using only some of the rat clocks (why is the brain so darn hard to fix? In this case, BBB barrier?) 15/n

      6 replies 8 retweets 187 likes
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    3. David Sinclair, PhD‏Verified account @davidasinclair May 11
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      Level of oxidative stress, and (wait for it) senescent cells were reduced "by a very considerable degree". Presumably, the immune system cleared the senescent cells. This is what the field is looking for. 16/n

      3 replies 15 retweets 234 likes
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    4. David Sinclair, PhD‏Verified account @davidasinclair May 11
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      The work shows, for the first time, that plasma fraction treatment reduces the epigenetic age of multiple tissues, and not by a little. What is in the plasma fraction that helps? Proteins, small chemicals, exosomes? 17/n

      2 replies 31 retweets 251 likes
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    5. David Sinclair, PhD‏Verified account @davidasinclair May 11
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      This reminds me of Fleming and Florey, who found an extract of penicillium mold could treat infections. There will be a race to find all these factors. http://www.alkahest.com  is already on the case. 18/n

      4 replies 23 retweets 245 likes
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    6. David Sinclair, PhD‏Verified account @davidasinclair May 11
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      So are the result believable? I see nothing wrong with the epigenetic clock analyses, the stats - Horvath is the best there is. It's also hard to see how the other measures could be messed up. Controls Sure, I'd like to see more controls, quantification of images, etc. 19/n

      4 replies 10 retweets 193 likes
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    7. David Sinclair, PhD‏Verified account @davidasinclair May 11
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      From what I can tell, the old control group didn't get injected with anything but saline. A better control would have been an injection of the old rats with old plasma fractions from rats of the same age, processed exactly the same way as the young plasma. 20/n

      4 replies 8 retweets 260 likes
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    8. David Sinclair, PhD‏Verified account @davidasinclair May 11
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      Expect a rush to India to get this treatment. I do hope Nugenics conduct careful human clinical trials first. In the US, young plasma treatments were stopped by the FDA until further notice citing a lack of proven safety. 21/n

      7 replies 19 retweets 243 likes
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    9. David Sinclair, PhD‏Verified account @davidasinclair May 11
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      If this finding holds up, rejuvenation of the body may become commonplace within our lifetimes, able to systemically reduce the risk of the onset of several diseases in the first place or provide resilence to a wide variety of infections. 22/n

      10 replies 48 retweets 444 likes
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    10. David Sinclair, PhD‏Verified account @davidasinclair May 11
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      It will be interesting to see if reprogramming factors, such as OSK, are induced in the tissues of treated animals. This might explain the ability to reset age. Maybe it's a different set of genes for each organ. We will see....! 23/n end.

      41 replies 19 retweets 333 likes
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      𝓓𝑎𝑛𝑖𝑒𝑙𝑙𝑒 𝓕𝑜𝑛𝑔, 𝕖𝕩-𝕡𝕣𝕠𝕕𝕚𝕘𝕪‏ @DanielleFong May 12
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      Replying to @davidasinclair

      @regardthefrost @nanogenomic @JimmyRis @Pravduh15 @SamoBurja @stewartbrand

      1:38 PM - 12 May 2020
      0 replies 0 retweets 0 likes

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