1986- early in HIV outbreak vaccine ”ready in 2 years” 34 years later still no vaccinepic.twitter.com/xQh8BjWy9U
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1986- early in HIV outbreak vaccine ”ready in 2 years” 34 years later still no vaccinepic.twitter.com/xQh8BjWy9U
HIV is a slightly different virus
1) HIV has much higher mutagenesis rates, 2) HIV entry in to cells is a series of protein-protein interactions and adhesions (mostly CD4). Whereas SARS-CoV-2 has a very clear entry mechanism: spike protein - ACE2 receptor.
Super informative! You know this much better than I do but wouldn’t the mutations have made it either better or worse? It seems it’s been consistent though
There are more than 10000 strains right now. The mutations are stable yet there are very many because it is so contagious and jumps species.
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