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Multiplexing is important for soft-real-time applications like voice/video calls. Even for a one-on-one call, it isn't suited to a single stream. If you don't receive the information in time, it's not relevant anymore, and the most recent information shouldn't be delayed for it.
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Also works well for handling multiple audio / video streams well at the same time without needing a connection for each. TCP is not very good even if you really do only need a single blocking stream and it's horrible for soft real time use cases like this. Result is not pretty.
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RTP and SCTP was also a great choice for bridging with existing stuff! Lots of telecom, RTSP etc... speaks all this stuff and really easy to connect now. Packets flow all the way through :) Not sure how bridging and QUIC will work out....
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