Excited to be part of the new "Centre for microbes, development and health", http://www.shanghaipasteur.cas.cn/CMDH/ headed by Phillippe Sansonetti, with several recent (and ongoing) international faculty hires. 2/10
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The centre will use large cohorts and a wide range of technologies to investigate the development of the infant gut microbiome, bringing a new degree of biological breadth and rigour to metagenomic studies. 3/10
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My group's research program http://sourcedb.shanghaipasteur.cas.cn/yw/Talent2016/PI2016/201911/t20191119_5438761.html … can be summarized by the phrase "trying to see the world from the point of view of a bacterium", based in the first instance on large genomic and metagenomic datasets. 4/10
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Bacteria face a wide variety of challenges, that they can use genetic variation to overcome. In highly recombining bacteria, coadaptation screens provide a novel and particularly powerful window into these strategies. Sets of genes that are found together function together. 5/10
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We are assembling datasets of tens of thousands of genomes from Helicobacter pylori and Vibrio parahaemolyticus. These species are particularly informative because of their recombination patterns. H. pylori also has a fascinating interaction with the host immune system. 6/10
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Will also do GWAS for pathogenicity, screens of antibiotic resistance, all the usual stuff and also studies with a more population genetic flavour, as we have done previously for both species, but on a more ambitious scale. 7/10
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We will also assemble a database of population genetic variation for thousands of bacterial species, from the human gut microbiome and elsewhere as well as developing statistical genetic methodology to analyze all of this data. 8/10
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The Chinese Academy of Sciences provides generous support to researchers at all levels: http://international-talent.cas.cn/front/pc.html#/bicsite/pifiIntroduce/pifi … so whether junior or senior, want a long or short stay, to work on these or other projects, or just hang out, do get in touch. daniel.falush@ips.ac.cn 9/10
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Shanghai is a great city, a point of intersection, with lots to do for everyone. e.g. I have been here a month and already been to my first psytrance festival https://shalanaya.org/ , and looking forward to Dragon Burn https://www.dragonburn.org So dont be shy, get in touch! 10/10
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Daniel congratulations!!! So happy for you, and super excited for the amazing research to come!
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