Does humanity benefit more from a single RCT with n=14,892 for something that does not work rather than 2 trials of n=7,446 that double the chances to find something useful? No. But British academic hubris is flattered be the unmatched size of its n.https://twitter.com/PeterHorby/status/1402244195943919616?s=20 …
RECOVERY result Aspirin
14892 COVID patients randomised to aspirin vs. usual care alone - no significant difference in 28-day mortality (17% aspirin vs. 17% usual care; rate ratio 0.96 [95% CI 0.89-1.04]; p=0.35). Pre-print imminent.
https://www.recoverytrial.net/news/recovery-trial-finds-aspirin-does-not-improve-survival-for-patients-hospitalised-with-covid-19 …
