Pr. Raoult's hospital has published the preprint of the cohort study of it 2,111 hospitalized patients. A few comments... https://www.mediterranee-infection.com/wp-content/uploads/2020/04/MS-2111-hospitalise%CC%81s-01062021.pdf …
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The eye-catchers are definitely in the subgroup analysis:pic.twitter.com/so2VcCsu3c
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The simple zinc-no zinc analysis yields no mortality benefit but the Hydoxychloroquine +Azythromicin +/- Zinc does, pointing to a large synergetic benefit. Confirmation of the role of HCQ as an active Zinc ionophore? Dr. Zelenko shall be pleased.pic.twitter.com/PQVP0jW84L
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Another surprise is the large negative impact of corticosteroids (mainly dexamethasone) on patients with low CRP (<100). The corticosteroid optimal point of intervention remains a real subject of investigation and the likely cause of the inconsistent observations.pic.twitter.com/uqIRD1CQbw
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Finally, more intriguing data in this original chart, suggesting that the efficacy HCQ+AZT is age dependent. Can we have the same chart for HCQ+AZT+Zc please? I ask because I wonder whether the strange rise & decline might be caused by a change in zinc deficiency by age/sex.pic.twitter.com/i2cMAqWBmL
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