Brazil has higher #SARSCoV2 incidence in more densely populated states. Little information on travel histories - early from Italy & Spain.
Basic R0 2.6-2.9 - but cases in urban areas spread to less populated locations.
#COVIDdynamics
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Again, 'disparities' make an appearance: higher income &
#COVID19 diagnosis - first introduced into high-income areas & spread to lower. Difficult to asses spread in lower-income areas; challenging to get accurate diagnoses. Unequal access skews picture.#COVIDdynamics2 odpowiedzi 1 podany dalej 1 polubionyPokaż ten wątek -
Brazil is 2nd highest in confirmed cases in world at 2.55 million cases
After interventions, R drops from 3 to 1-1.6
Incredibly, first case went from sampling to sequence & report in only 48 hours!! An incredible achievement!
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@nmrfaria has detected over 100 introductions, & 3 main clades in Brazil - where majority of sequences cluster. It's possible to see the transition from within & between state transmission - international imports move to local transmission. Most are within state!#COVIDdynamics1 odpowiedź 2 podane dalej 2 polubionePokaż ten wątek -
Finally we come to our final talk in an absolutely fantastic day -
@Tuliodna will take us back across the ocean to Africa, to hear about#SARSCoV2 spread in Africa - a fitting way to finish the session!#COVIDdynamics1 odpowiedź 1 podany dalej 2 polubionePokaż ten wątek -
@Tuliodna, sporting a fantastic new moustache
, outlines some of his main questions: Can we estimate # introductions into Africa, and when, how, & where did community transmission happen? Which lineages? And can we use genome data to control & prevent outbreaks?
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South Africa leads the pack for sequencing in Africa, but throughput is improving! At the moment, can measure >300 introductions into Africa, but potentially 1000s - limited by seq data. Mostly from Europe (80%), but early intro from Asia & later from Americas.
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Highlighting a few South Africa clusters - an introduction from Netherlands spread rapidly in a supermarket in Cape Town. Can spot a few distinct cluster expansions like this! These serve as amplification events that can fuel larger spread.
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Like so many places, we see in South Africa that early introductions were mostly 19A (Nextstrain clades), giving way to 20A and 20B.
@Tuliodna finishes reminding that controlling the epidemic is paramount - do not want 'rolling waves' of cases!#COVIDdynamics1 odpowiedź 0 podanych dalej 4 polubionePokaż ten wątek -
And that's a wrap!! I really am totally blown away by the fantastic speakers we had today

And a *huge* thank you to my amazing co-chairs @MorganeMRolland &@alison_l_hill! And to head organizer Maureen Helinski - this wouldn't have happened without her!pic.twitter.com/Tk0KH2ne2n
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Thanks to all of you for making this happen.
Wydaje się, że ładowanie zajmuje dużo czasu.
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