True. But what if the confirmed cases are only a fraction of the total number of infected people?
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W odpowiedzi do @C_Althaus @ChristoPhraser
Isn’t that pretty much a given, at this stage?
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W odpowiedzi do @BigFernowski @C_Althaus
Do you have data that shows this? I think the distribution of severity of infection is still largely undocumented. We don't know what fraction of infection are being missed.
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The only indicator I know of is in comparing the number of reported cases to the back-calculated estimates from
@MRC_Outbreak https://www.imperial.ac.uk/media/imperial-college/medicine/sph/ide/gida-fellowships/2019-nCoV-outbreak-report-22-01-2020.pdf … Whilst this does imply under-reporting of infections, it doesn't indicate that cases are a 'tiny fraction' of number infected.1 odpowiedź 0 podanych dalej 0 polubionych -
W odpowiedzi do to @ChristoPhraser@BigFernowski i jeszcze
But that is only an indicator. I expect we will see more estimates based on follow up contact studies soon.
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W odpowiedzi do to @ChristoPhraser@BigFernowski i jeszcze
If this is quoted correctly https://www.theguardian.com/science/2020/jan/26/coronavirus-could-infect-100000-globally-experts-warn … , then
@MRC_Outbreak may have increased their estimates substantially, so you may be right. My guess is that this will become clearer in the next couple of days.1 odpowiedź 0 podanych dalej 1 polubiony -
Their earlier estimates were based on a much smaller number of exported cases around mid January. There are now over 50 exported cases. So it’s quite likely that epidemic in China is much larger than confirmed cases suggest.
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Yes OK: 50 now vs. 7 at the time of writing, so if the central estimate was 4000 then, it should be ~28,000 now, give or take. If the upper confidence interval was 9,700 then, it should be ~70,000 now. Which is the same order as magnitude as the quoted figure.
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W odpowiedzi do to @ChristoPhraser@C_Althaus i jeszcze
But for the preprint, they report on 830 confirmed cases by 23 Jan. What do you think that should be compared to? ~8000?? That would indicate ~10% of infections being reported.
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440 confirmed cases in China by January 21, and 7 confirmed cases with symptom onset on or before January 18 gave total size between 1,000 and 9,700 cases. Now, numbers in China and abroad are roughly 7 times higher, so total size roughly between 7,000 and 70,000?
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But better to rerun the numbers properly.
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Of course. These are very rough guesstimates.
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