A very useful addition to the large number of preprints posted in the last few days. Thanks for sharing so quickly. At first read, this seems to employ a range of robust methods to estimate R - 2.9, 95% CI 2.3-3.7 - and a useful like-for-like comparison with SARS2002https://twitter.com/biorxivpreprint/status/1221529332369281024 …
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Isn’t that pretty much a given, at this stage?
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Do you have data that shows this? I think the distribution of severity of infection is still largely undocumented. We don't know what fraction of infection are being missed.
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Absolutely, that's an important point. We should be cautious in jumping to conclusions. If most infections become cases, then the improvements in isolation seen in Figure 3B will have a dramatic impact. But we currently have little idea of how many infections are diagnosed.
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The interaction between clinical spectrum, health seeking behaviour, clinical services, diagnostic capacity, reporting and modelling future trends is very complex, any estimates are so provisional. Seem to be a ome worrying parameters compared to SARS at the moment
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