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CT_Bergstrom's profile
Carl T. Bergstrom
Carl T. Bergstrom
Carl T. Bergstrom
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@CT_Bergstrom

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Carl T. BergstromVerified account

@CT_Bergstrom

#BlackLivesMatter Information flow in bio, society, & science. Book *Calling Bullshit*: http://tinyurl.com/y7ekfkhx  I love crows and ravens. he/him

Duwamish Lands (Seattle)
ctbergstrom.com
Joined June 2015

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    1. Carl T. Bergstrom‏Verified account @CT_Bergstrom 21 May 2020

      With guidance from this newly released CDC document, federal agencies are modeling the COVID pandemic using implausibly low fatality rate. Their "best estimate" has a symptomatic CFR of 0.4% Their worst case scenario has CFR — not IFR — of 1% https://www.cdc.gov/coronavirus/2019-ncov/hcp/planning-scenarios.html …pic.twitter.com/C4tGpsykHj

      101 replies 592 retweets 1,113 likes
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    2. Carl T. Bergstrom‏Verified account @CT_Bergstrom 21 May 2020

      Their best estimate of the CFR for people over 65 is 1.3%, and the worst case scenario is 3.2%. I'd love to know how these estimates were obtained, given that they are being used for government planning and recommended to modelers everywhere. h/t @RAVerBruggen, @AndreasShruggedpic.twitter.com/vGv2pJsDLl

      13 replies 110 retweets 427 likes
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    3. Carl T. Bergstrom‏Verified account @CT_Bergstrom 21 May 2020

      The more I think about it, the more this bothers me. These numbers are so far outside of the scientific consensus that this strikes me as a devious and cynical effort to manipulate not only federal modeling but the broader scientific discourse.

      54 replies 363 retweets 1,199 likes
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    4. Carl T. Bergstrom‏Verified account @CT_Bergstrom 21 May 2020

      People are asking me what the IFR ranges ought to be. That's tricky and depends in part on the purpose of the models for which the parameters are intended. That said, I'd want to span the range of reasonable estimates, and I want a point estimate that in accord with such.

      3 replies 34 retweets 202 likes
      Show this thread
    5. Carl T. Bergstrom‏Verified account @CT_Bergstrom 21 May 2020

      The CDC estimates do not seem to be doing that. Here's one reasonable (IMO) systematic review of IFR estimates. https://www.medrxiv.org/content/10.1101/2020.05.03.20089854v2 … John Ioannidis has lower ranges here https://www.medrxiv.org/content/10.1101/2020.05.13.20101253v1.article-metrics …, but I don't find them credible; see https://twitter.com/GidMK/status/1262956011872280577 …pic.twitter.com/erhe41abOV

      7 replies 56 retweets 220 likes
      Show this thread
    6. Carl T. Bergstrom‏Verified account @CT_Bergstrom 21 May 2020

      Imperial College Report 23, released today, estimates IFR for all US states. Almost all of the CDC's parameter range falls well below the almost all of the probability mass in the Imperial estimates. https://www.imperial.ac.uk/mrc-global-infectious-disease-analysis/covid-19/report-23-united-states/ …pic.twitter.com/nDKHooag1V

      12 replies 103 retweets 290 likes
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    7. Carl T. Bergstrom‏Verified account @CT_Bergstrom 21 May 2020

      Update: fixed the decimal place for the CDC "best estimate":pic.twitter.com/gCYN6eXk1Z

      19 replies 45 retweets 170 likes
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    8. Carl T. Bergstrom‏Verified account @CT_Bergstrom 22 May 2020

      CNN reports on the CDC's parameters. https://www.cnn.com/2020/05/22/health/cdc-coronavirus-estimates-symptoms-deaths/index.html …pic.twitter.com/hkzFgzBAXG

      12 replies 47 retweets 181 likes
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      Carl T. Bergstrom‏Verified account @CT_Bergstrom 22 May 2020

      For people who don't like the Imperial College numbers, here is the CDC's parameter range overlaid against the data from the meta-analysis cited above (https://www.medrxiv.org/content/10.1101/2020.05.03.20089854v2.full.pdf …)pic.twitter.com/FqbwSFPv8o

      5:21 PM - 22 May 2020
      • 36 Retweets
      • 158 Likes
      • Thatcher Ulrich Lyndie Federico Gueli Paula Rogness Hussain Ali Dominique Heinke Amanda Makulec MPH David S Chang 🇹🇼🧢🍎 Silent Raven
      11 replies 36 retweets 158 likes
        1. New conversation
        2. Carl T. Bergstrom‏Verified account @CT_Bergstrom 28 May 2020

          Followup from @RAVerBruggen:https://www.nationalreview.com/corner/why-does-the-cdc-think-the-covid-19-fatality-rate-is-so-low-and-why-wont-it-tell-anyone/ …

          8 replies 26 retweets 74 likes
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        3. Carl T. Bergstrom‏Verified account @CT_Bergstrom 11 Jul 2020

          The CDC has updated their IFR estimates to a range of 0.5-0.8%, with a best guess of 0.65%. These seem reasonable to me, they reflect current consensus thinking, and I'm pleased to see this. h/t @geoffmpricehttps://www.cdc.gov/coronavirus/2019-ncov/hcp/planning-scenarios.html#table-1 …

          30 replies 127 retweets 324 likes
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        4. Carl T. Bergstrom‏Verified account @CT_Bergstrom 11 Jul 2020

          Of course IFR not a universal constant; it varies by location according to demographics, risk factors, mode of transmission and viral load, etc. It could end up being higher in some places, or lower in others. But the range 0.5-0.8% seems good for e.g. a 25%-75% confidence range.

          12 replies 9 retweets 77 likes
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        5. Carl T. Bergstrom‏Verified account @CT_Bergstrom 11 Jul 2020

          I'd been saying 0.5-1.5% for several months. In general, IFR estimates seem to have be converging on the lower half of this range, perhaps dipping lower domestically due to the demographic skew of cases during US reopening. Unfortunately as older people are infected, it can rise.

          8 replies 7 retweets 64 likes
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        6. Carl T. Bergstrom‏Verified account @CT_Bergstrom 11 Jul 2020

          One recent paper estimates an IFR toward the top end of my 0.5-1.5% range in NYC during its first wave. I have not spent enough time with this paper to have a strong judgment about that value, but want to share it for context.https://www.medrxiv.org/content/10.1101/2020.06.27.20141689v1 …

          15 replies 11 retweets 41 likes
          Show this thread
        7. End of conversation
        1. Jennifer Mitchel‏ @drjenmitchel 22 May 2020
          Replying to @CT_Bergstrom

          So... the CDC took the approx. average of the three lowest estimates, ignored the rest, and slapped a "best estimate" bow on that? Am I reading this right? 👀

          0 replies 1 retweet 7 likes
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        2. Social Distancing Cat‏ @CriticalCricket 22 May 2020
          Replying to @CT_Bergstrom

          I think the Imperial College numbers represents a worse case scenario; however, the worst case is exactly how you should plan.

          1 reply 1 retweet 3 likes
        3. Show replies
        1. New conversation
        2. Wes Pegden‏ @WesPegden 22 May 2020
          Replying to @CT_Bergstrom

          If the CDC was claiming an IFR it would reasonable, and in line with the published estimates in this meta-analysis (the higher estimates come from preprints). What makes it seem like a real stretch is claiming it's a s-CFR. And they don't even define what counts as symptomatic?

          2 replies 0 retweets 12 likes
        3. Newman Nahas‏ @NahasNewman 22 May 2020
          Replying to @WesPegden @CT_Bergstrom

          They are using CFR in a nonstandard way (ie to mean IFR and not crude CFR). Wouldn’t be first time. The nomenclature is far from consistent. Their usage is apparent from their definition. Denominator = # experiencing symptoms from infection, NOT casespic.twitter.com/2BLwTaKq4w

          2 replies 1 retweet 9 likes
        4. Show replies

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