I hope further exposés on the lethal incompetence of @chesaboudin hits the newspapers, the situation is out of control.
Can SF continue without an effective DA ? No.
Should Mr Boudin resign immediately? Absolutely yes.
I don't live there so this is an outsiders thought on the situation. Boudin was elected, which includes the consequences of his actions. You guys can try to remove him, but at this point I think he would be replaced with even further left.