John Briggs

@BriggsGroup

Briggs group at MRC-LMB Cambridge. Cryo-EM, tomography, subtomogram averaging, CLEM, coated vesicles, enveloped viruses.

Vrijeme pridruživanja: srpanj 2016.

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  1. Prikvačeni tweet
    29. sij

    ’s work on structures and interactions of AP2 and clathrin within coated vesicles, now posted on . Collaboration with , Bernard Kelly and David Owen at . Work done at & .

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  2. proslijedio/la je Tweet
    27. sij

    Take a look at our new story in on the conserved role of IP6 in lentivirus assembly. It was real fun to work on this with and many others.

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  3. 27. sij

    We enjoyed working with and on their beautiful structures of immature EIAV Gag lattices, revealing a conserved role for IP6 in lentivirus assembly. Out now in

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  4. proslijedio/la je Tweet
    23. sij

    The first structure of a domesticated viral-like Arc capsid provides a basis for understanding a novel means of neuronal communication and memory formation

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  5. 21. sij

    Here is a News and Views from about 's recent paper on Arc capsids (). Written by Vivian Budnik and Travis Thomson:

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  6. 8. sij
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  7. 7. sij

    Structures of virus-like capsids made by the neuronal Arc proteins. 's paper is now out in . This was a fun collaboration with and . Work done at .

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  8. 3. lis 2019.

    Postdoc position available jointly between the and labs at to develop automated data acquisition and on-the-fly processing procedures for sample screening and assessment.

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  9. 22. kol 2019.

    It was a lot of fun to have on sabbatical in the lab this summer, and we are excited that we will continue working together. Thanks Erica!

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  10. 19. kol 2019.

    Postdoc position available in my group - methods development for cryo-electron tomography and subtomogram averaging.

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  11. 19. kol 2019.
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  12. 11. srp 2019.

    See also work on dArc1 in this preprint from Ian Taylor : Structure of D. melanogaster ARC1 reveals a repurposed molecule with characteristics of retroviral Gag

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  13. 4. lip 2019.
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  14. 14. svi 2019.

    Lauren Ann's paper (previously on bioRxiv) online at MaM: Fluorescence-Based Detection of Membrane Fusion State on a Cryo-EM Grid using Correlated Cryo-Fluorescence and Cryo-Electron Microscopy

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  15. proslijedio/la je Tweet
    14. svi 2019.

    Struggling with sample spreading? Can you see your particles in low mag maps? Then you might want to try our SerialEM workflow for efficient data collection using virtual maps of sample areas.

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  16. proslijedio/la je Tweet
    3. svi 2019.

    A cryoEM structure of the yeast Ty3 capsid from is day 123 of . Ty3 is a retrotransposon – a self-replicating genetic element. It is a cousin of the human retrovirus HIV-1 which makes similar capsids, and of a neuronal protein Arc1.

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  17. 30. tra 2019.

    The immature capsid of the yeast retrotransposon Ty3 looks rather like the mature capsid of its distant relative, the HIV-1. Our paper from in collaboration with Suzanne Sandmeyer is online now:

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  18. 30. tra 2019.

    The 2019 symposium is live-streaming here with lots of interesting talks on the schedule for today and tomorrow.

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  19. 9. sij 2019.

    Our new manuscript on bioRxiv: Multiplexed electron microscopy by fluorescent barcoding allows screening for ultrastructural phenotype

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  20. 27. stu 2018.

    Kun's work on the structure and maturation of MLV is now online: "Structure and architecture of immature and mature murine leukemia virus capsids"

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  21. 22. stu 2018.

    Application deadline is approaching for these positions in the EM facility .

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