Those who argue that large scale randomized controlled trials are the only reliable evidence in evidence based medicine have misled you. Now you can see why—large RCTs amplify systematic error in addition to signal, whereas meta-analysis amplifies signal, and corrects for error.
-
-
@TimPoolClips - you have been noticed my friend.Thanks. Twitter will use this to make your timeline better. UndoUndo
-
-
-
It kinda looks like the remaining evidence is pretty damned weak, Bret. Be careful out there.
Thanks. Twitter will use this to make your timeline better. UndoUndo
-
-
-
You should see the article The Guardian posted about this... They seem to have missed your main point entirely.https://www.theguardian.com/science/2021/jul/16/huge-study-supporting-ivermectin-as-covid-treatment-withdrawn-over-ethical-concerns …
- Show replies
New conversation -
-
-
Do we need ivermectin if we have vaccines?
Thanks. Twitter will use this to make your timeline better. UndoUndo
-
-
-
Assuming this study disproportionately powers the meta analyses to their positive results - it is no small wound to the overall body of evidence …. no?
-
That's the thing, this particular study was not the star focus in the meta analysis.
- Show replies
New conversation -
-
-
The meta analyses very much rest on it!
Thanks. Twitter will use this to make your timeline better. UndoUndo
-
-
-
Not with your help they won't!
Thanks. Twitter will use this to make your timeline better. UndoUndo
-
-
-
Similarly flawed RCT papers saying ivermectin is NOT effective. The lesson?RCTs are always vulnerable to multiple sources of manipulation. Let’s embrace population studies & observational clinical data eg: rs Tyson, Varon etc - no space for deceptionhttp://www.thedesertreview.com/tncms/asset/editorial/df5674ee-d530-11eb-98a1-3fc9e8ddc005 …
Thanks. Twitter will use this to make your timeline better. UndoUndo
-
Loading seems to be taking a while.
Twitter may be over capacity or experiencing a momentary hiccup. Try again or visit Twitter Status for more information.