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Fascinating story and a well-characterized chemical probe!
@thesgconline@Merckhttps://twitter.com/CherylArrowsmi1/status/1206919080445431811 …
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This is a realy nice data repository!https://twitter.com/targetvalidate/status/1176508058035544066 …
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Jark Boettcher proslijedio/la je Tweet
@ChemHaWei@D_B_McConnell@jsrosenblum and colleagues go after tough cancer metabolism target PHGDH with#FBLD and#HTS to generate inhibitor BI-4924 and its ester prodrug BI-4916 that can disrupt serine biosynthesis@JMedChem https://tinyurl.com/yy72cnowHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Happy to share that the chemical probe BI-9321 and the related negative control BI-9466 described in Nature Chemical Biology (https://lnkd.in/gsSynty ) are now available via opnMe (https://lnkd.in/gDvpSGb ).
@thesgconline@chembiohub@CSHL@UNCPharmacyhttps://twitter.com/koester_markus/status/1178613184208556032 …
0:15Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Great visualisation and in spite of significant progress still some work ahead.https://twitter.com/mattschap/status/1176228653518262274 …
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Jark Boettcher proslijedio/la je Tweet
Haresh Ajani
@thesgconline assesses a virtual screening method customized for#PROTACs.#Openscience notebook: http://bit.ly/2kbnyWU Blog: http://bit.ly/2lKbOLy pic.twitter.com/v0X9vSJZMD
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Jark Boettcher proslijedio/la je Tweet
See news article today on
#Target2035. https://www.nature.com/articles/d41573-019-00159-9 … Imagine the discoveries that could be made for health and medicine if we had a pharmacological modulator for every protein. Join us in the effort@thesgconline#opensciencepic.twitter.com/2ELyy9U325
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Jark Boettcher proslijedio/la je Tweet
Knowledge on purifying larger protein complexes and on looking at them on an atomar level with X-ray crystallography or EM would complete the profile.
@boehringer#oncology https://boehringer-ingelheim.talentry.com/app/talent/s/TYBsBNKdpKpWsuD2Lx8abx/jobs/110992/details …https://twitter.com/MSamwer/status/1161959683206406144 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Congrats to the team of
@thesgconline and@UNCPharmacy for the discovery and characterization of a chemical probe for NSD2-PWWP1https://twitter.com/thesgconline/status/1161283055270682624 …
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Grear summary of the FBS approaches performed to obtain the chemical probe BI-9321 by Dan Erlanson
@PracticalFrag@thesgconline@CSHL@UNC@chembiohub@ChrisVakochttps://twitter.com/PracticalFrag/status/1153294607754489857 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
The chemical probe for the PWWP1 domain of NSD3 (BI-9321) is available via the SGC homepage (https://lnkd.in/gdGUbfT ). The joint publication of scientist from
@thesgconline,@UNC ,@CSHL, and@Boehringer describing the discovery and characterization is now online.https://twitter.com/nchembio/status/1148622591218868224 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi
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