Some fun weekend reading from group meeting: A survey of the chemistry and cool structures from recent heroes of drug discovery (2015-2019): https://baranlab.org/wp-content/uploads/2019/12/FDA-Approved-Drugs-2015-2019-Group-Meeting.pdf …
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And since many of us have an extra day off, here's one more from this weekend: A lesson in strategy often overlooked in many synthesis classes: MACROCYCLIZATION! https://baranlab.org/wp-content/uploads/2020/01/macrocyclizations.pdf …
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Bonus points for ending with a PKD quote
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Is this a review from the old Hive forum / Rhodium chemistry archive? Well done! The crazy backyard process chemistry makes you laugh and think at the same time.
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Just skimmed it. Love the coverage of Shulgin compounds! People with a background in Medicinal or Organic Chem. would love PIHKAL. Not simply for the memoirs on a body of SAR research, but for the late great Prof. Shulgin's witty and fascinating commentary along the way.
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All that for just one group meeting??? Wow!
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