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B_resnick's profile
Brian Resnick
Brian Resnick
Brian Resnick
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@B_resnick

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Brian ResnickVerified account

@B_resnick

Science reporter @voxdotcom: psychology, stars, nature, health, and “whoa that’s cool.” http://www.vox.com/authors/brian-resnick …

Washington, DC
brian-resnick.com
Joined May 2011

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    1. Brian Resnick‏Verified account @B_resnick Oct 22

      Genetics research is overwhelmingly conducted on white participants of European ancestry. That's a big problem for medicine. https://www.vox.com/science-and-health/2018/10/22/17983568/precision-medicine-genetics-gwas-diversity-all-of-us …pic.twitter.com/sNCxPGJUE3

      32 replies 72 retweets 142 likes
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    2. Brian Resnick‏Verified account @B_resnick Oct 22

      There is interesting debate over whether polygenic risk assesments will ever truly be clinically useful (beyond risk assesments conducted today.) But as it stands, those assesments won't be equitable, working on everyone.

      1 reply 0 retweets 2 likes
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    3. Brian Resnick‏Verified account @B_resnick Oct 22

      There are important things not to confuse here. Genetic risk scores derived from Europeans don't translate as well to other people. That's **not** because we're so biologically different. Or because race is a "biological construct."

      5 replies 0 retweets 2 likes
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    4. Brian Resnick‏Verified account @B_resnick Oct 22

      It's because the differences that signal risk from one group to a next, are teeny tiny, a bit arbitrary, and not always directly linked to the casual pathway that translates genes to disease.

      5 replies 1 retweet 4 likes
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    5. Brian Resnick‏Verified account @B_resnick Oct 22

      If anything, it's another example of how wonderfully complex our genomes are, how useful human variation can be, and how the small differences between us, though tiny, still can matter when it comes to health.

      3 replies 0 retweets 1 like
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    6. The Russocrat‏ @Russocrat Oct 22
      Replying to @B_resnick

      Is there a chance that some tiny group in South America (or wherever) might have unique defenses to a given disease that are totally unknown in European groups? Such that by not studying them, they're missing out on breakthrough discoveries?

      1 reply 0 retweets 0 likes
      Brian Resnick‏Verified account @B_resnick Oct 22
      Replying to @Russocrat

      yes! I discuss that in the piece.

      7:59 AM - 22 Oct 2018
      • 1 Like
      • The Russocrat
      1 reply 0 retweets 1 like
        1. The Russocrat‏ @Russocrat Oct 22
          Replying to @B_resnick

          "We need to explore human genetic diversity to make game-changing insights. This is something people may misunderstand about evolution: Species survive because of diversity. When change comes, there’s someone, somewhere, who can help our species survive..." excellent article thx

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