I was on the fence on this. I'm not anymore. Here's why. 1. More contagious strains are now >1/3 of all US cases. And new evidence confirms B117 causes more severe disease, with MUCH higher rates of severe illness and death at younger ages.https://directorsblog.nih.gov/author/collinsfs/ …
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2. Rising cases require more commitment to masks, testing, indoor limits. But the recurring pattern here and abroad is many people and local leaders won't tighten these until too late. And 11% of us attended large events in last 24h, almost 2x early Jan. https://delphi.cmu.edu/covidcast/survey-results/?date=20210327 …pic.twitter.com/twZf5lWPR3
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3. The vaccines work against B117. While Europe is in another surge of cases and deaths due to it, UK and Israel are not, because of high levels of at least first-dose vaccination.https://twitter.com/allahpundit/status/1376867035515326464?s=20 …
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4. We have evidence of strong effectiveness after a single dose. A new CDC MMWR study found mRNA vaccines reduced risk of COVID19 infection among health care & other essential workers by 80% after the 1st dose and 90% following the 2nd dose.https://www.cdc.gov/mmwr/volumes/70/wr/mm7013e3.htm?s_cid=mm7013e3_w …
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5. I had concerns that dose sparing protocols could result in development of variants that evade vaccine protection. Preliminary evidence, however, suggests it's very unlikely -- indeed "such strategies should slow the rate of vaccine or immune escape." https://dash.harvard.edu/handle/1/37366988 …
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We must still follow basic steps for 6-10 weeks more: masks, testing, no big indoor events. They work, as seen in hospitals & schools abroad. But we must speed vaccination now. Pushing 2nd doses to 12 weeks like the UK will do that. And I believe the country is ready for it.
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We definitely need to now get the younger cohort vaccinated.
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Your tweet reminded me of this tweet
https://twitter.com/vb_jens/status/1372251931444350976?s=20 …
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We are on the 12wk delayed 2nd dose protocol here in the UK. I’m an NHS doctor and having my 2nd Vax tomorrow. It is going well for us here
sending love to all in USA.
Also, on another note I love your books. Checklist manifesto especially. Brilliance 
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I’ll have to get that one. LOVED Being Mortal!!
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