Genetic correlations with IQ. (Data from Savage et al, 2018)pic.twitter.com/IUQg0R8PiV
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Genetic correlations with IQ. (Data from Savage et al, 2018)pic.twitter.com/IUQg0R8PiV
I have marked the doi for future reading, but I am surprised at the + corr between IQ and autism, as the mean IQ of Asperger syndrome is slightly below avarage (cf. among others Wechsler, 2014), and that of Infantile autism carrying a greater risk for Intellectual Disability.
At least some of it seems to be diagnostic heterogeneity (as revealed by, yes, genetic correlations):https://www.biorxiv.org/content/early/2017/11/27/224774 …
1/I think there is a real need to standardize diagnoses for these large studies. We are wasting much effort! There are already validated, reliable, short tests for depression, etc. (HAM-D) -- and, further, the phenotypes reported are often based on categories too fuzzy or ill
2/specified to be useful. Autism is a good example. ASD really describes a number of distinct disorders, in terms of etiology - the category may be useful for insurance codes, but we are losing granular info in this context.
I agree, but on the other hand, you can go a long way with noisy cheap measurements. With IQ, it turned out to be most efficient to just use 'years of education' - a crude measurement of a crude proxy. It's not easy to get more fine-grained measurements which can split better!
I just want to spend the $10bn or whatever it would cost to give the WAIS-R to public school 8th graders and get it over with!
Welp, there's always the Scandinavian draft IQ tests and biobanks and population registries...
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