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China National Health Commission reports latest
#coronavirus update for 2/4 http://www.nhc.gov.cn/xcs/yqfkdt/202002/17a03704a99646ffad6807bc806f37a4.shtml … - Confirmed cases +3887: 20438
24324
- Suspected cases: 23214
23260
- Severe cases +431: 2788
3219
- Deaths +65: 425
490
- Discharged +262: 632
892
#2019nCoVpic.twitter.com/gZWD2C2cCE
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$FTSV underwhelming data for anti-CD47 magrolimab + PD1 combo in solid tumor in ASCO-SITC abstract 0% ORR in 18 ovarian cancer patients https://meetinglibrary.asco.org/record/183103/abstract …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Whoa, that NEJM report from Germany claiming asymptomatic transmission of
#coronavirus turned out to be wrong The index patient did have symptoms while in Germany. German RKI has written a letter to NEJM to set the record straight https://www.sciencemag.org/news/2020/02/paper-non-symptomatic-patient-transmitting-coronavirus-wrong …https://twitter.com/AndyBiotech/status/1223068735398928385 …
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Sad news and shows how challenging vaccine development is… when you read all those PRs re
#coronavirus vaccine Another#HIV vaccine strategy fails in large-scale study https://www.sciencemag.org/news/2020/02/another-hiv-vaccine-strategy-fails-large-scale-study … “There’s absolutely no evidence of efficacy”… despite encouraging Ph2 data in NEJMpic.twitter.com/djrwgFVuOA
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“The worst symptom of
#coronavirus is racism.” Sad to see this outbreak has divided us more as a human race...#2019nCoV doesn’t discriminate. This is a war between species, we should all stick together to fight this nasty bug, now more than ever...https://twitter.com/DocSchmadia/status/1222706344739909633 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Multiple reports now confirm
#coronavirus detected in fecal samples, suggest high likelihood of fecal-oral transmission https://www.bloomberg.com/news/articles/2020-02-01/coronavirus-lurking-in-feces-may-reveal-hidden-risk-of-spread … Hopefully we won't see a repeat of Amoy Gardens "super-spreading" tragedy during SARS outbreak in Hong Kong... https://link.springer.com/chapter/10.1007/978-94-007-4192-8_13 …pic.twitter.com/0XMc54p1Fv
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Here we go... That "uncanny"
#coronavirus/HIV preprint has been voluntarily withdrawn by its authors, per bioRxiv Co-Founder@cshperspectives https://twitter.com/cshperspectives/status/1223689222667804673 … For more details on its technical flaws, check out this very helpful thread by@trvrb https://twitter.com/trvrb/status/1223667905927139328 …pic.twitter.com/cGRoerx38i
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Everyone interested in that
#coronavirus/HIV preprint should read this debunking piece https://theprepared.com/blog/no-the-2019-ncov-genome-doesnt-actually-seem-engineered-from-hiv/ … It's unfortunate this sloppy work was widely spread and adding fuel to bioweapon conspiracy theories even though it may never pass peer-review in any serious journal...Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
NEJM report out describing first case of
#Wuhan#coronavirus in the United States Notably, the patient’s clinical condition improved after treatment of$GILD remdesivir (GS-5734) https://www.nejm.org/doi/full/10.1056/NEJMoa2001191 …#2019nCoVpic.twitter.com/X00Ht8mzbn
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NEJM report from Germany formally documents first case of asymptomatic transmission of
#Wuhan#coronavirus during the incubation period https://www.nejm.org/doi/full/10.1056/NEJMc2001468?query=featured_home …#2019nCoVpic.twitter.com/kyLuLspsOe
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#Wuhan#coronavirus has now officially exceeded SARS in cumulative cases…in only one month https://twitter.com/AndyBiotech/status/1223034675901476865 … There're some complacency due to relatively low death rate so far, let's just all hope#2019nCoV fatality rate won't creep up like SARS did https://endlessmetrics.substack.com/p/pandemic-its-still-early …pic.twitter.com/GeNJ1sWZN1
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China National Health Commission reports latest
#coronavirus update for 1/30: http://www.nhc.gov.cn/xcs/yqfkdt/202001/a53e6df293cc4ff0b5a16ddf7b6b2b31.shtml … - Confirmed cases: 7711
9692
- Suspected cases: 12167
15238
- Severe cases: 1370
1527
- Death toll: 170
213
#2019nCoVpic.twitter.com/cjJNsWnvvR
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Very interesting work in
@nature today showing ex-smokers have ~4X more genetically healthy cells than smokers, helping to protect them against lung cancer https://www.nature.com/articles/s41586-020-1961-1 … Take home message -- Never too late to quit https://www.sanger.ac.uk/news/view/never-too-late-quit-protective-cells-could-cut-risk-lung-cancer-ex-smokers …pic.twitter.com/dJA9BxUeA9
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NEJM new paper out analyzing data on the first 425 confirmed cases in
#Wuhan#coronavirus outbreak https://www.nejm.org/doi/full/10.1056/NEJMoa2001316?query=featured_home … - median age ~59yo - 56% male - mean incubation period ~5.2 days (95% CI, 4.1 to 7.0) - basic reproductive number R0 ~2.2 (95% CI, 1.4 to 3.9)#2019nCoVpic.twitter.com/KRmajNdQk6
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Largest clinical data set from initial cases of
#Wuhan#coronarovirus just published online at@TheLancet https://marlin-prod.literatumonline.com/pb-assets/Lancet/pdfs/S0140673620302117.pdf … Includes 99 patients with#2019nCoV, 49 (49%) had a history of exposure to the Huanan seafood market. 11% died, 31% discharged so far.pic.twitter.com/mzbHWvZ4mf
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#2019nCoV New study using travel history and symptom onset of 34 confirmed cases outside#Wuhan estimates the mean incubation period for the novel#coronavirus to be 5.8 (4.6 – 7.9, 95% CI) days, in line with SARS and MERS https://www.medrxiv.org/content/10.1101/2020.01.27.20018986v1 …pic.twitter.com/6TCA7tTWWV
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Lenvatinib + PD1 combo bring some of the most encouraging data at
#GI20 for tough to treat cancers 70% ORR in MSS Gastric cancer https://twitter.com/oncologician/status/1220559144488321025 … 77% ORR in unresectable HCC https://meetinglibrary.asco.org/record/182285/abstract … Will$CLVS lucitinib achieve something similar? https://ascopubs.org/doi/pdf/10.1200/JCO.19.01598 …pic.twitter.com/Xyw7TtI2Z6
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#2019nCoV China reports confirmed cases +39% to total 2744; Death toll +43% to total 80 http://www.nhc.gov.cn/xcs/yqfkdt/202001/3882fdcdbfdc4b4fa4e3a829b62d518e.shtml … With#Wuhan#coronavirus spreading to >10 countries in 4 continents, only sensible for@WHO to declare PHEIC now. Over-reaction better than under-reaction at this pt!pic.twitter.com/76A4botoMw
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The medical staff risking their lives fighting
#2019nCoV at the frontline are the real heroes! Great news that 11 medical staff at#Wuhan Union Hospital have turned negative for the novel#coronavirus and clinical symptoms were controlled after treatment! http://www.xinhuanet.com/politics/2020-01/26/c_1125504283.htm …pic.twitter.com/WuvIjDqROF
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