A good number of backend services are significantly influenced by syscall performance. Anything where individual requests are handled quickly and a lot of requests can be made in a short time will see impact.
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Apache serves perhaps?
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In my experience full blown browser<->server communication is likely going to be over a too high latency link, and not be sufficiently CPU bound, to make this a big issue. So sure, you can probably can construct a workload, but I think it's not going to be a super common problem.
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