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Prikvačeni tweet
I am thrilled to announce I'm starting my lab
@BrandeisU this fall. The Bisson Lab will investigate the cellular organization and cytoskeleton dynamics in the astonishing archaeal world. Keep an eye out for open positions - and our website filled with cool movies like thesepic.twitter.com/kJ8dZw2FqAPrikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Alex Bisson proslijedio/la je Tweet
Nice overview of the diversity of motile systems throughout the Tree of Life. Many of which, sadly, do not involve
#myosin.pic.twitter.com/9Z2vR4EGEo
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Alex Bisson proslijedio/la je Tweet
Video of our proposed hypothetical model for eukaryogenesis—the “Entangle-Engulf-Endogenize (E3)” modelhttps://www.youtube.com/watch?v=_kvGaNyz014&feature=emb_logo …
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Alex Bisson proslijedio/la je Tweet
Here is the next iteration of the "cells to scale" poster, now featuring microtubules! Thanks to all who contributed (names listed at bottom of image). Want to learn more about these organisms? There's a Gordon Conference for that! https://www.grc.org/plant-and-microbial-cytoskeleton-conference/2020/ … https://twitter.com/KatrinaVelle/status/1203680710340550657 …pic.twitter.com/3GSr29w25P
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Alex Bisson proslijedio/la je Tweet
I want to end by reiterating that organelle biology in bacteria and archaea is an area that is ripe for exploration. You can read our recent review for a perspective on the importance of studying the cell biology of organelles in bacteria and archaea.https://www.annualreviews.org/doi/full/10.1146/annurev-cellbio-100616-060908?url_ver=Z39.88-2003 …
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Alex Bisson proslijedio/la je Tweet
1.For science to work for everyone, scientific meetings need to be affordable. Otherwise we create a situation where we enhance inequalities & promote the already privileged. Case in point: I have noticed a worrying upward trend in the cost to attend a number of society meetings.
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Alex Bisson proslijedio/la je Tweet
Let’s improve visibility and career opportunities for women in the field of cryo-electron microscopy! I started a network on Academondo (http://www.Academondo.com ). If you want to join- just sign up and then ask to join the ‘Women in CryoEM’ network!
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Alex Bisson proslijedio/la je Tweet
Excited for this story to be out! Made possible by excellent collaborations with
@HummelsKate@JenniChlebek@ViollierPat lab Nicolas Biais lab and Ankur Dalia!https://twitter.com/IUBiology/status/1207385518285164544 …
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Alex Bisson proslijedio/la je Tweet
Postdoctoral position available in the Absalon Lab. Don't hesitate to DM me for more informationpic.twitter.com/fjdfqvVQsq
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Feel free to write us with your rants, suggestions, and any kind of questions! Preprints are awesome because of that and this would definitely make our story better for the peer-reviewed version! Finally, wanted to thank everyone in the Bisson, Pohlschroder, and Pfeiffer labs!
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8) And here is our cartoon model coupling cell-wall processing, phospholipid processing, and cell elongation. But too many questions are still up in the air. What is going on with the S-layer array during these shape transitions? Or what is the driven force behind cell growth?pic.twitter.com/WdojTXhz0B
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7) As these proteins don't play a role in cell division at all, we propose these enzymes "hijack" the cytokinetic ring to promote cell envelope remodeling at midcell. In layman's terms, these guys grow from the middle! To prove that, we GFP-tagged the S-layer protein itself:pic.twitter.com/ocscDf46KD
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6) They even "follow" the cytokinetic ring during cell division:pic.twitter.com/mpQW9EA6hR
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5) But how cells organize this processing in space and time? To answer that, we GFP-tagged these enzymes and to our surprise, they all localize to the division site - where the cytoskeletal FtsZ polymer assemble the cytokinetic ring!pic.twitter.com/w3ASk2jFUh
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4) Farid went further and showed that without phospholipid modification, cells were unable to either process S-layer proteins and anchor them to the membrane. That means that attachment of surface proteins requires both substrate and activation of the membrane!pic.twitter.com/PX7TyJs7wg
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3) In this work, Farid observed a genomic correlation between the genes encoding the sortase responsible to anchor the S-layer to the membrane and 2 enzymes predicted to process and modify phospholipids. Intriguingly, when he deleted these genes, cells were all rod-shaped!pic.twitter.com/9vWiHJ9aeD
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2) Did I talk about cell shape? Haloarchaea are talented in regards to assuming different shapes. They are capable of developing and switch back and forth between disks and rods. But how do S-layer and other envelope compartments rearrange to accommodate such fast transitions?pic.twitter.com/XSue2OeNxc
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1) Mecky has been studying archaeal surface protein biogenesis. For example, they did some great work on the S-layer anchoring mechanism to membrane phospholipids. This is really important for cell shape, as S-layer is the main archaeal cell wall component (yes, no PG here!)
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I'm so proud of this paper. It's my first correspondent author's work. It's my first paper with
@pohlschr, who I met only recently and hit off so quickly! And it's scientifically delightful as it demonstrates how archaeal cells teach us new tricks. Here are the take-home msgshttps://twitter.com/biorxivpreprint/status/1202366151382228993 …Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Alex Bisson proslijedio/la je Tweet
Vikash
@viktzv is presenting a poster on augmin-mediated microtubule branching@ASCBiology. Here is a cool video from his poster, visit his poster (B165 on Monday, December 9, 2019) to see more exciting stuff!#ASCBEMBO19pic.twitter.com/bfXxtS1DDPHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Alex Bisson proslijedio/la je Tweet
We updated the academic job market preprint! We took a deeper look at "interplay between metrics" and provided more clarity to the lack of alignment between applicant and search committee values.
@FuturePI_Slack#postdoc#academicjobshttps://www.biorxiv.org/content/10.1101/796466v2 …Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi
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