The most uncomfortable flight I ever had was when i got seated between two friends. Neither one wanted the middle seat, so they sat in the aisle and window seats and talked across me the whole flight.
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I was once on a three-hour train trip next to my gf and across from a stranger whose knees were literally between mine.
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Same time with you between friend that best thing to do runs forests stay out of it my opinion for my on experience
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"Would you like to switch seats so you can talk to each other without interruption? Because you are about to start being frequently interrupted."