Yes, for example, people on this very thread here have stated that because of the representation of autistic people which is usually white, cis, and male, a lot of women and girls have struggled to get diagnosed as autistic. This has caused real barriers and harm.
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In my latest study Into disability representation there were only 14 autistic characters out of 708 disabled characters and both of the main characters were played by nondisabled actors. Autistic people are not even welcome to play themselves.
Is this proportional to the population?
I also don't see why an actor should have anything in common with who they're portraying. I don't personally feel like I have any more right to act as an autistic woman than a neurotypical woman does.