I used to think some people have different tolerances for LSD that come from unknown, unchangeable configurations of their brain. , for example, could take 700ug and function like I do on 100ug. I figured he probably just had a brain that didn't 'feel' LSD as much-
Conversation
but he ended up having a shift in the way he related to LSD and himself, and now doses affect him at the typical intensities you'd expect.
This makes me think people who have lowered response to LSD might actually be able to change that somehow, consciously.
Replying to
“The psychedelic experience” by metzner and Leary suggest that first timers should take doses in the 400-600 ug range and that the experienced can take 200 to experience the full depth of lsd
1
Replying to
a hike with intense topography; some people have insecurities going in, others don't; then "something profound and unanticipated happens" whether its a spill down a hill or you're better at it than you ever knew; going back to hike again, you notice the topography more either way
Replying to
Do you know of people who've done the reverse, or can alter response intensity at will?
Replying to
Self-report; yes entirely. This is exactly what my Psilocybin experiences have been like.