I used to think some people have different tolerances for LSD that come from unknown, unchangeable configurations of their brain. @rothosphere, for example, could take 700ug and function like I do on 100ug. I figured he probably just had a brain that didn't 'feel' LSD as much-
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I tend to think psychometrically/analytically about this. I think high doses for the uninitiated may cause an increase in openness that allows for a lessening of resistance to ego death when further lower doses are taken
End of conversation
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“The psychedelic experience” by metzner and Leary suggest that first timers should take doses in the 400-600 ug range and that the experienced can take 200 to experience the full depth of lsd
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a hike with intense topography; some people have insecurities going in, others don't; then "something profound and unanticipated happens" whether its a spill down a hill or you're better at it than you ever knew; going back to hike again, you notice the topography more either way
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1000% agree with you because it happened to me.
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Do you know of people who've done the reverse, or can alter response intensity at will?
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Self-report; yes entirely. This is exactly what my Psilocybin experiences have been like.
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