Beautiful work, Adrien! Any plans for compatibility with outputs from tombo and/or megalodon?
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Nope! :D I will definitely not support Tombo as ONT has repeatably said they will stop developing at some point. Megalodon maybe, but I haven't had the time to try yet. I know that Nanopolish is more complicated, but IMO it's the most robust and well maintained option
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For more advanced visualization and functional elements analysis see also https://github.com/wdecoster/methplotlib … from
@wouter_decoster. I think the 2 tools works well together, with pycoMeth running the genome-wide analysis and methplotlib to validate and visualize genes or enhancers.Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi
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Nice tool. Are there plans to implement support for Guppy basecaller directly detected basemods? CG is nice, but there are a lot more to be explored in other symmetrical and non-symmertrical basemods
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Thanks. I am not planning to implement any other tools ATM. I am well aware that ONT has developed a few options for DNA meth (Guppy, Megalodon and Tombo) but it is unclear to me how they compare and which way they will push forward.
@ewanbirney@The__Taybor ?
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Looks very promising
, keen to give it a try over the coming weeks!Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi
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