I’m going through a bunch of comparative transcriptomics & genomics papers purporting to find genes associated with aging by looking at either which genes are overexpressed in young vs old animals, or highly mutated between long-lived vs short-lived species.
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A mouse lifespan study with 100 mice is about $200k, $400k with thermoneutral housing. This doesn’t count the cost of genetic modification.
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why $200K? Our housing cost is about $0.1/mouse/day in shared cages, so (rounding up) about $5K/yr for 100 mice. So if a mouse lives 4 yrs then that's $20K for 100 mice.
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however expensive it is in mice, it would certainly be cheaper in daphnia! wonder if anyone's working on that :)
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Yep! It’s also been done in worms.
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