A leading geneticist recently asserted to me that we can store a person's genome in ~2 megabytes simply by encoding all deviations from a complete reference genome. Curious if others see any caveats, and what challenges for analysis this approach might present?
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Surely someone has calculated the entropy of the human genome, no ?
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0.02 bits per base = 10 megabytes here buthttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083090/#__ffn_sectitle …
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