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AdamMarblestone's profile
Adam Marblestone
Adam Marblestone
Adam Marblestone
@AdamMarblestone

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Adam Marblestone

@AdamMarblestone

Technologist, Scientist

adammarblestone.org
Joined February 2009

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    1. Adam Marblestone‏ @AdamMarblestone 16 Jul 2019
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      • Report NetzDG Violation

      Adam Marblestone Retweeted Antonio Regalado

      Sewing-machine insertion of flexible electrodes via small holes. Good progress on channel count + insertion, building on @m8ta's work. Also nice chip+packaging. Hard stuff. Much depends on gliosis, but Chong Xie's results promising. Laser would indeed be preferable to drill. 1/4https://twitter.com/antonioregalado/status/1151335093354582016 …

      Adam Marblestone added,

      Antonio RegaladoVerified account @antonioregalado
      omfg, neuralink give exclusive to new yorkt imes who calls it "baby steps" . 1,500 neurons in a rat. https://www.nytimes.com/2019/07/16/technology/neuralink-elon-musk.html?login=email&auth=login-email …
      Show this thread
      2 replies 10 retweets 35 likes
      Show this thread
    2. Christian Wentz‏ @ChristianWentz 17 Jul 2019
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      Replying to @AdamMarblestone @m8ta

      🤦🏻‍♂️ if you’re putting electronics inside the skull, flexible electrodes will lose long term to optical readout. Nearly all hard problems unsolved here, animal model doesn’t translate (vasculature, insertion depth), hermeticity, reg burden unproven. Feel like we’ve been here...

      1 reply 1 retweet 3 likes
    3. Andrew Hires‏ @AndrewHires 17 Jul 2019
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      Replying to @ChristianWentz @AdamMarblestone @m8ta

      Optical readout has problems too. Need to express sensor genes stably and safely. Can't see more than 200um deep without 2-photon, which is not getting minaturized to a wearable probably ever. Even with 2p, can't get over 700um deep. Implantable lenses cause huge damage...

      2 replies 0 retweets 5 likes
    4. Christian Wentz‏ @ChristianWentz 14 Aug 2019
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      Replying to @AndrewHires @AdamMarblestone @m8ta

      2-photon and sensor genes are not the only options here...

      1 reply 0 retweets 1 like
    5. Andrew Hires‏ @AndrewHires 14 Aug 2019
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      Replying to @ChristianWentz @AdamMarblestone @m8ta

      ...unless you want cellular resolution instead of measuring blood flow/oxygenation...

      1 reply 0 retweets 0 likes
    6. Adam Marblestone‏ @AdamMarblestone 14 Aug 2019
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      Replying to @AndrewHires @ChristianWentz

      pic.twitter.com/Jxm5MZPzQB

      1 reply 0 retweets 0 likes
    7. Andrew Hires‏ @AndrewHires 14 Aug 2019
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      Replying to @AdamMarblestone @ChristianWentz @m8ta

      Willing to consider other plausible mechanisms with citation. (e.g. photoacoustic imaging of activity dependent contrast agent with resolution enhanced via adaptive optics corrected by ultrasound-induced cavitation guidestars...). A TED talk is not a citation. What u got?

      1 reply 0 retweets 2 likes
      Adam Marblestone‏ @AdamMarblestone 14 Aug 2019
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      Replying to @AndrewHires @ChristianWentz @m8ta

      Agreed. I wish we could continue this in detail...! There are a lot of smart people thinking outside the box at Kernel and elsewhere though...

      11:49 AM - 14 Aug 2019
      • 2 Likes
      • KordingLab 👨‍💻🧠∇🔬📈,🏋️‍♂️⛷️🏂🛹🕺⛰️☕🦖 Andrew Hires
      0 replies 0 retweets 2 likes

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