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  1. proslijedio/la je Tweet
    30. sij

    You know how hypothalamic function declines with age? This paper seems to isolate an essential mechanism for that, and shows that it can be reversed. (In mice, of course.)

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  2. proslijedio/la je Tweet
    30. sij
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  3. proslijedio/la je Tweet
    29. sij

    This is important bc one of the biggest arguments pharma makes against price control of new medicines by US Govt and quicker generic medicines access is that the cost to develop the new drug would be larger than the predicted ROI of the drug

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  4. 29. sij
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  5. 29. sij

    Also this is my childhood dog, finally explaining why the Doge meme triggered such a profound response in me

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  6. 29. sij

    Rare non-science tweet due to recent archival discovery: Photographic evidence strongly suggests my personality development peaked around age 11, and has slowly declined since. Note my offering the cat an entire McDonalds hamburger and putting the rat in my bro’ hat.

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  7. 29. sij

    This paper is so insightful. Surprised how much mileage they could gain out of such a simple setting.

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  8. proslijedio/la je Tweet
    29. sij

    VERY important paper from Logothetis' group just posted on about decoding consciousness in PFC in monkeys during a no-report paradigm. VERY critical data for current debates in awareness.

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  9. proslijedio/la je Tweet
    29. sij

    'Using NEURON for Reaction-Diffusion Modeling of Extracellular Dynamics' // 'Development of credible clinically-relevant brain simulations has been slowed due to a focus on electrophysiology...neglecting multi-scale whole-tissue modelling...'

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  10. proslijedio/la je Tweet
    29. sij

    , a : At least since Francis Crick’s famous review of 1979, neuroscientists have dreamed of ways to identify all the neurons connected to a cell of interest. In the last decade this has become a reality through the widespread use of rabies virus tracers. 1/11

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  11. proslijedio/la je Tweet
    29. sij
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  12. proslijedio/la je Tweet
    28. sij

    New paper: Towards a Human-like Open-Domain Chatbot. Key takeaways: 1. "Perplexity is all a chatbot needs" ;) 2. We're getting closer to a high-quality chatbot that can chat about anything Paper: Blog:

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  13. proslijedio/la je Tweet
    29. sij

    Today I will be teaching my undergrad course "How to build a brain from scratch" for the 2nd year running. I've put the materials online - include a document with all lecture slides and notes, which is about as long as a decent novel. Enjoy!

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  14. proslijedio/la je Tweet
    29. sij

    Predictive Routing: "There are no special error-detection circuits or mechanisms." There are instead pathways that are gated by predictions and thus can be activated by unexpected inputs. Amazing monkey electrophysiology work by Andre Bastos

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  15. proslijedio/la je Tweet
    28. sij

    this is a neat idea - DIY neuropeptide signaling HySyn: A genetically-encoded synthetic synapse to rewire neural circuits in vivo

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  16. proslijedio/la je Tweet
    27. sij

    Epic's call to block a proposed data rule is wrong for many reasons, by and ⁦⁩ in ⁦

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  17. proslijedio/la je Tweet

    CAR-T cells for solid tumors: there's a new target, Claudin-6. And combination with an RNA vaccine delivering Claudin-6 to immune cells boosts their function in mouse models of cancer

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  18. proslijedio/la je Tweet
    23. sij

    This paper on the lab culturing of "the closest living relatives of the ancient archaeal host cells from which eukaryotes are thought to have evolved" is pretty fab. These seem like rather weird cells.

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  19. proslijedio/la je Tweet
    26. sij

    I used to love reading the CS Monitor in print for it's consistent and balanced global coverage. Exited to be in their cover feature. Thanks to Simon for a thoughtful article

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  20. proslijedio/la je Tweet
    27. sij

    Congrats for your first first author paper 👏👏👏 Conventional assumptions involving the speed of radar waves in snow introduce systematic underestimates to sea ice thickness and seasonal growth rate estimates

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