You know how hypothalamic function declines with age? This paper seems to isolate an essential mechanism for that, and shows that it can be reversed. (In mice, of course.)https://twitter.com/aginghighlights/status/1222965066850603009 …
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It's likely! I think we should be studying interventions on animals that are longer lived for their size than mice. (Porcupines & squirrels, for instance.)
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OTOH we know that humans don't have *all* the long-life switches turned on, because there are animals that live longer than us (some tortoises & whales) and animals that don't get cancer (elephants) or senescence at all (naked mole rats).
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Some; but evidence from calorie restriction suggests that we are not as optimized as we could be. But in general it's harder to extend lifespan the more long lived an animal is (See the difference between improvement for worms vs mice)
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Yeah, also, those are critters where extending their fertility into a more abundant time is useful, humans, not so much. I'm hopeful, but trying to stay grounded.
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Čini se da učitavanje traje već neko vrijeme.
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