time for another #tweeprint:
This #preprint about a particular SHAPE of seizure is live:https://www.medrxiv.org/content/10.1101/2020.01.09.20017053v1 …
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We show this spectral broadening associated with seizing brain tissue can be clearly observed in the spectrum, or measured for each discharge in a seizure using information theoretic quantities.pic.twitter.com/EdPmeOmfmT
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Finally, back to that narrowband gamma, we show that action potentials measured on the microelectrode arrays differentially couple to narrowband gamma before and after the neuronal signature of recruitment into a seizure.pic.twitter.com/rgTOwKtloB
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These analyses were inspired by work from
@LMPrida's lab and further confirm that broadening of the high frequency LFP spectrum is associated with increased population neuronal firing under an electrode, even if that electrode may not be able to record action potentials.Prikaži ovu nit -
These results further emphasize the importance of examining the high frequency LFP spectrum to contextualize seizure recordings in epilepsy research and point to broadband high frequency LFP's utility for understanding seizure mechanisms in the clinical setting.
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