Elliot Smith

@50kDinar

research faculty studying human neurons, epilepsy, and neural prostheses; also musician. He/him.

Salt Lake City, UT
Vrijeme pridruživanja: kolovoz 2011.

Medijski sadržaj

  1. 13. sij

    Finally, back to that narrowband gamma, we show that action potentials measured on the microelectrode arrays differentially couple to narrowband gamma before and after the neuronal signature of recruitment into a seizure.

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  2. 13. sij

    We show this spectral broadening associated with seizing brain tissue can be clearly observed in the spectrum, or measured for each discharge in a seizure using information theoretic quantities.

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  3. 13. sij

    Note the clear narrowband gamma peak in the above spectrogram, and the increased broadband high frequency LFP after about 40 seconds. The narrowband gamma doesn't distinguish seizing brain tissue, but the broadening of the spectrum in later discharges does.

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  4. 13. sij

    First, early discharges are more broadly spatially distributed on ECoG, even more widespread than the later discharges that are associated with intense action potential firing, and phase-locked high frequency LFP that indicates seizing brain tissue.

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  5. 13. sij

    In this preprint, we used microeletrode array and ECoG recordings of human seizures to contextualize the clinically used LFP with action potential recordings. Can we see differences that would imply early inhibitory discharges?

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  6. 13. sij

    There are a bunch of studies in brain slices (picture from Trevelyan et al. 2007) showing that some of these early discharges are inhibitory.

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  7. 10. sij
    Odgovor korisniku/ci
  8. 2. sij

    Y’all otter check out this video! – mjesto: Singapore Botanic Gardens

  9. 27. pro 2019.

    Saw some forest people

  10. 26. pro 2019.

    Palm frond eclipse

  11. 25. pro 2019.

    Merry Christmas from Pulau Pinang

  12. 22. pro 2019.
  13. 13. stu 2019.
    Odgovor korisniku/ci
  14. 8. stu 2019.

    I recreated a supplementary movie from Schevon et al. (2016) NatComms showing the neuronal and LFP dynamics of human seizure expansion (also Smith et al. (2016) NatComms). So cool that the Utah Array allows for this tiny, pixelated picture of what's happening in the human brain!

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  15. 24. lis 2019.
    Odgovor korisnicima

    But does your data fit the model?

  16. 16. lis 2019.
    Odgovor korisnicima

    My high school biology teacher did this (full tuck though). Just happened to be the day he was lecturing on flies.

  17. 16. lis 2019.

    Come check out me and my science pals at !

  18. 4. lis 2019.
    Odgovor korisnicima

    awesome paper! The first figure is super rad! It reminds me of 80's style portraits:

  19. 30. ruj 2019.

    As with previous studies, we found few neurons encoded that interference with their firing rates (though more in the cingulate). However, many more neurons encoded the interference with the timing of their action potentials, relative to the population activity. 5/n

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  20. 30. ruj 2019.

    The task creates a state of cognitive interference, while we recorded, brain activity from the prefrontal cortex, which is often implicated in control, specifically the anterior cingulate cortex and lateral prefrontal cortex. 4/n

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