Important letter from Michael Biggs, deconstructing a study (Costa et al) being used to claim puberty blockers improve psychological functioning. No statistically significant difference between blocked/unblocked kids. https://www.jsm.jsexmed.org/article/S1743-6095(19)31424-9/fulltext …
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It highlights the difference between treatment group and control is small, not statistically significant, even if it was, the magnitude of improvement is tiny to risk such a major intervention, it’s disturbing that this is touted as support for treating with puberty blockers
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